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首页> 外文期刊>Pharmaceutical Chemistry Journal >ANTIOXIDANT PROPERTIES OF SULFUR-CONTAINING BIOLOGICALLY ACTIVE SUBSTANCES STUDIED BY VOLTAMMETRIC AND SPECTROPHOTOMETRIC TECHNIQUES
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ANTIOXIDANT PROPERTIES OF SULFUR-CONTAINING BIOLOGICALLY ACTIVE SUBSTANCES STUDIED BY VOLTAMMETRIC AND SPECTROPHOTOMETRIC TECHNIQUES

机译:伏安和分光光度法研究的含硫生物活性物质的抗氧化剂性能

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摘要

Sulfur-containing biologically active substances (BAS) demonstrate pronounced antioxidant properties. Glutathione, cysteine, cystine, methionine, taurine, and lipoic acid occupy special positions among sulfur-containing antioxidant compounds. The antioxidant properties of these sulfur-containing BAS have been characterized and analyzed using voltammetric and spectrophotometric data. All studied BAS showed more or less pronounced antioxidant activity. Lipoic acid and glutathione exhibited the maximum antioxidant activity, which agrees with data published in the literature. Methionine showed the minimum antioxidant activity among the group of investigated BAS. The antioxidant activity was compared on the basis of the international criterion of antioxidant properties of sulfur-containing BAS, oxygen radical absorbance capacity (ORAC) with respect to a reference antioxidant (glutathione). A correlation was found between results of the voltammetric and spectrophotometric analyses.
机译:含硫的生物活性物质(BAS)具有明显的抗氧化性能。谷胱甘肽,半胱氨酸,胱氨酸,蛋氨酸,牛磺酸和硫辛酸在含硫的抗氧化剂化合物中占据特殊的位置。这些含硫的BAS的抗氧化性能已通过伏安和分光光度数据进行了表征和分析。所有研究的BAS或多或少都显示出明显的抗氧化活性。硫辛酸和谷胱甘肽具有最大的抗氧化活性,这与文献中公布的数据一致。在所研究的BAS组中,蛋氨酸显示出最小的抗氧化活性。根据含硫BAS的抗氧化性能的国际标准,相对于参考抗氧化剂(谷胱甘肽)的氧自由基吸收能力(ORAC)来比较抗氧化活性。在伏安和分光光度分析的结果之间发现相关性。

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