PHYSICOCHEMICAL PROPERTIES OF AND ANALYTICAL METHOD FOR THE ORIGINAL ANXIOLYTIC SUBSTANCE GB-115

V. S. Klumova; L. N. Grushevskaya; N. I. Avdyunina; B. M. Pyatin; M. S. Sergeeva; L. M. Gaevaya; M. E. Dudenkova

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PHYSICOCHEMICAL PROPERTIES OF AND ANALYTICAL METHOD FOR THE ORIGINAL ANXIOLYTIC SUBSTANCE GB-115

机译：原始无毒物质GB-115的理化性质和分析方法

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GB-115 is an original peptide anxiolytic with the structure N-(6-phenylhexanoyl)glycyl-L-tryptophan amide that has been developed at Zakusov State Institute of Pharmacology (Moscow). The physicochemical properties of GB-115 parent substance were studied. Analytical procedures for it were elaborated. General pharmacopoeial quality characteristics have been determined. UV, IR, and NMR spectra have been measured. A method for determining foreign impurities in GB-115 parent substance that is based on HPLC was developed.

机译：GB-115是一种具有N-（6-苯基己酰基）甘氨酰基-L-色氨酸酰胺结构的抗焦虑肽，已在扎库索夫州立药理研究所（莫斯科）研发。研究了GB-115母体的理化性质。详细的分析程序。已确定一般药典质量特征。已经测量了UV，IR和NMR光谱。提出了一种基于HPLC的GB-115母体杂质检测方法。

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《Pharmaceutical Chemistry Journal》 |2011年第10期|共4页
作者
V. S. Klumova; L. N. Grushevskaya; N. I. Avdyunina; B. M. Pyatin; M. S. Sergeeva; L. M. Gaevaya; M. E. Dudenkova;
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正文语种 eng
中图分类药学;
关键词
GB-115 anxiolytic; pharmaceutical analysis; HPLC; IR spectroscopy; UV spectroscopy.;

机译：GB-115抗焦虑药理分析HPLC红外光谱紫外光谱;

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1. PHYSICOCHEMICAL PROPERTIES OF AND ANALYTICAL METHOD FOR THE ORIGINAL ANXIOLYTIC SUBSTANCE GB-115 [J] . V. S. Klumova, L. N. Grushevskaya, N. I. Avdyunina, Pharmaceutical Chemistry Journal . 2011,第10期

机译：原始无毒物质GB-115的理化性质和分析方法
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PHYSICOCHEMICAL PROPERTIES OF AND ANALYTICAL METHOD FOR THE ORIGINAL ANXIOLYTIC SUBSTANCE GB-115

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