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首页> 外文期刊>Pharmacology, Biochemistry and Behavior >Stress hormonal factors, fatigue, and antioxidant responses to prolonged speed driving.
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Stress hormonal factors, fatigue, and antioxidant responses to prolonged speed driving.

机译：压力荷尔蒙因素，疲劳和抗氧化剂对长时间开车的反应。

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摘要

Oxygen free radicals have been implicated in exercise-induced cell and tissue injury, indicating an oxidative stress. Fatigue accompanied by a number of physiological and metabolic changes is in indication of overtraining. This study aimed to examine the influence of a continuous 24-h intermittent speed driving (1 h driving/1 h stop), on the response of hormones, antioxidative factors, lipid, and enzyme levels. Seven race car drivers of national level were examined before, during, and immediately after the trial of speed driving on a test designed to check endurance to stress. The parameters measured were: testosterone (Tes), cortisol (Cor), IgM, IgA, cholesterol, HDL, billirubin, ceruloplasmin, urea, uric acid, creatine kinase, and transaminases. Stress hormone Cor declined significantly (p < 0.05), while Tes did not change significantly. Fatigue enzyme, aspartate transaminase (GOT) increased significantly (p < 0.05), while alanine transaminase (GPT) did not change and urea declined. Muscle enzyme, creatine kinase (CK) increased to sixfold (p < 0.01). IgA, IgM and lipids did not change. The primary antioxidant ceruloplasmin increased significantly (p < 0.001), while antioxidants uric acid and glucose remained unchanged. Among the factors measured, ceruloplasmin, cortisol, urea, GOT, and CK seem to give a picture of the organism's alertness and defence capabilities in conditions of stress and fatigue.
机译：氧自由基与运动引起的细胞和组织损伤有关，表明存在氧化应激。疲劳伴随着大量的生理和代谢变化表明过度训练。这项研究旨在研究连续24小时间歇性速度行驶（1小时行驶/ 1小时停止）对激素，抗氧化因子，脂质和酶水平的响应的影响。在进行高速驾驶试验之前，之中和之后，对7名国家级别的赛车手进行了检查，以检查其耐压性。测得的参数为：睾丸激素（Tes），皮质醇（Cor），IgM，IgA，胆固醇，HDL，Billirubin，铜蓝蛋白，尿素，尿酸，肌酸激酶和转氨酶。应激激素Cor显着下降（p <0.05），而Tes没有明显变化。疲劳酶，天冬氨酸转氨酶（GOT）显着增加（p <0.05），而丙氨酸转氨酶（GPT）不变且尿素下降。肌肉酶肌酸激酶（CK）增加到六倍（p <0.01）。 IgA，IgM和脂质没有改变。初级抗氧化剂铜蓝蛋白显着增加（p <0.001），而抗氧化剂尿酸和葡萄糖保持不变。在测得的因素中，铜蓝蛋白，皮质醇，尿素，GOT和CK似乎可以说明生物体在压力和疲劳条件下的机敏性和防御能力。

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