Transdermal nicotine: single dose effects on mood, EEG, performance, and event-related potentials.

Knott V; Bosman M; Mahoney C; Ilivitsky V; Quirt K

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Transdermal nicotine: single dose effects on mood, EEG, performance, and event-related potentials.

机译：透皮尼古丁：单剂量影响情绪，脑电图，表现和与事件相关的电位。

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A 21-mg dose of nicotine was administered transdermally to 16 overnight smoking-deprived smokers in a double-blind, placebo-controlled design. Mood ratings, electroencephalography (EEG), behavioral performance and event-related potential (ERP: P300) indices of attention and information processing speed were assessed before and 4 h after placeboicotine treatment. Although nicotine, relative to placebo, failed to alter mood, it increased absolute and relative power indices of EEG arousal, shortened reaction times, and increased P300 amplitudes. The results are discussed in relation to nicotine's actions on cholinergic transmission and its role in smoking behavior.

机译：采用双盲，安慰剂对照设计，对16名通宵吸烟的夜间吸烟者进行了21 mg剂量的尼古丁经皮给药。在安慰剂/尼古丁治疗之前和之后4小时，评估情绪等级，脑电图（EEG），行为表现和事件相关电位（ERP：P300）的注意力指数和信息处理速度。尽管相对于安慰剂，尼古丁不能改变情绪，但它增加了唤醒脑电图的绝对和相对功率指数，缩短了反应时间，并增加了P300振幅。讨论了有关尼古丁对胆碱能传播的作用及其在吸烟行为中的作用的结果。

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《Pharmacology, Biochemistry and Behavior》 |1999年第2期|共9页
作者
Knott V; Bosman M; Mahoney C; Ilivitsky V; Quirt K;
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正文语种 eng
中图分类药理学;
关键词
Affect; Electroencephalography; Event-Related Potentials; P300; Nicotine; 情感; 脑电描记术; 事件相关电位; P300; 烟碱; 精神运动性行为;

机译：Affect;Electroencephalography;Event-Related Potentials;P300;Nicotine;情感;脑电描记术;事件相关电位;P300;烟碱;精神运动性行为;

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1. Transdermal nicotine: single dose effects on mood, EEG, performance, and event-related potentials. [J] . Knott V, Bosman M, Mahoney C, Pharmacology, Biochemistry and Behavior . 1999,第2期

机译：透皮尼古丁：单剂量影响情绪，脑电图，表现和与事件相关的电位。
2. Effects of nicotine on visuo-spatial selective attention as indexed by event-related potentials. [J] . Meinke A, Thiel CM, Fink GR Neuroscience: An International Journal under the Editorial Direction of IBRO . 2006,第1期

机译：尼古丁对视觉空间选择性注意的作用，以事件相关电位为指标。
3. Modulation of Mood and Cognitive Performance Following Acute Administration of Single Doses of Melissa Officinalis (Lemon Balm) with Human CNS Nicotinic and Muscarinic Receptor-Binding Properties [J] . Neuropsychopharmacology . 2003,第10期

机译：急性服用具有人中枢神经系统烟碱和毒蕈碱受体结合特性的蜜蜂issa（柠檬膏）单剂量后的情绪和认知能力调节
4. An ex-vivo and in-vivo performance of a switchable carbon nanotube membrane device for transdermal nicotine delivery [C] . Gaurav Kumar Gulati, Lily Berger, Bruce Jackson Hinds Annual TechConnect World Innovation Conference Expo;Annual Nanotech Conference Expo;National SBIR/STTR Conference . 2017

机译：用于透皮尼古丁递送的可切换碳纳米管膜装置的体外和体内性能
5. Acute effects of transdermal nicotine on EEG and mood during short-term smoking deprivation. [D] . Bosman, Melissa A. 1996

机译：短期吸烟剥夺过程中，经皮尼古丁对脑电和情绪的急性影响。
6. EARLY NICOTINE WITHDRAWAL AND TRANSDERMAL NICOTINE EFFECTS ON NEUROCOGNITIVE PERFORMANCE IN SCHIZOPHRENIA [O] . Christopher G. AhnAllen, Paul G. Nestor, Martha E. Shenton, -1

机译：早期尼古丁戒断和经皮尼古丁对精神分裂症患者神经认知功能的影响
7. Acute effects of transdermal nicotine on EEG and mood during short-term smoking deprivation. [O] . M. Bosman -1

机译：短期吸烟剥夺期间透皮尼古丁对脑电图和情绪的急性作用。

Transdermal nicotine: single dose effects on mood, EEG, performance, and event-related potentials.

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