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首页> 外文期刊>Pharmacology, Biochemistry and Behavior >Blood cholesterol levels of 32-year-old alcohol consumers are better than of nonconsumers.
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Blood cholesterol levels of 32-year-old alcohol consumers are better than of nonconsumers.

机译：32岁酒精饮料消费者的血液胆固醇水平要高于非消费者。

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Blood cholesterol levels are expected to be important factors in the causal pathway between alcohol consumption and CHD. The relation between alcohol consumption and blood cholesterol levels is investigated in 130 men and 145 women aged 32.4 years old (+/-1.0), from the Amsterdam Growth and Health Longitudinal Study. When controlled for gender, cholesterol levels at age 13.1 years, and lifestyle at adult age (smoking, physical activity, dietary habits), no significant differences were found for total cholesterol (TC) levels between alcohol consumers and nonconsumers. Serum high-density lipoprotein (HDL) cholesterol levels were 0.12 mmol/l higher in subjects consuming >/=100 grams of alcohol per week than in nonconsumers (p < 0.05). Regression coefficients of subjects consuming 10 to 50, or 50 to 100 g alcohol per week did not differ statistically from those of nonconsumers. The positive relation between alcohol consumption and serum HDL was modified by smoking (found in nonsmokers, but not in smokers). No differences between beer, wine, and spirits were found for their relation with serum HDL. In conclusion, 32.4-year-old nonsmoking subjects who consumed >/=100 g of alcohol per week had improved HDL levels compared with nonconsumers, whereas the protective effect of drinking smaller amounts of alcohol did not reach statistical significance.
机译：血液胆固醇水平有望成为饮酒与冠心病之间因果关系的重要因素。根据阿姆斯特丹生长与健康纵向研究，对年龄为32.4岁（+/- 1.0）的130位男性和145位女性中的酒精摄入与血液胆固醇水平之间的关系进行了研究。在控制性别，13.1岁时的胆固醇水平和成年后的生活方式（吸烟，体育锻炼，饮食习惯）后，饮酒者和非消费者之间的总胆固醇（TC）水平没有显着差异。每周摄入> / = 100克酒精的受试者的血清高密度脂蛋白（HDL）胆固醇水平比非消费者高0.12 mmol / l（p <0.05）。每周饮用10至50或50至100 g酒精的受试者的回归系数与非消费者的回归系数无统计学差异。饮酒与饮酒与血清高密度脂蛋白之间的正相关关系通过吸烟改变（在非吸烟者中发现，但在吸烟者中没有）。啤酒，葡萄酒和烈性酒与血清HDL的关系没有发现差异。总而言之，与非消费者相比，每周饮酒> / = 100 g的32.4岁不吸烟受试者的HDL水平有所改善，而饮酒量较少的保护作用没有统计学意义。

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