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首页> 外文期刊>Pharmacology, Biochemistry and Behavior >Environmental influences on brain neurotrophins in rats.
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Environmental influences on brain neurotrophins in rats.

机译：环境对大鼠脑神经营养蛋白的影响。

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摘要

Environmental factors can have profound influences on the brain. Enriching environments with physical, social and sensory stimuli are now established to be beneficial to brain development and ageing. A multitude of responses from cellular and molecular mechanisms to macroscopic changes in neural morphology and neurogenesis have been considered in the context for evidences that environmental inputs can regulate brain plasticity in the rat at all stages of life. Data from our laboratory have revealed that enriched environment increased nerve growth factor (NGF) gene expression and protein levels in the hippocampus, and this may contribute to events underlying environmentally induced neural plasticity. Because neurotrophic factors are essential for neural development and survival, they are likely to be involved in the cerebral consequences modified by enriched experiences.
机译：环境因素可能对大脑产生深远影响。现在建立了具有身体，社交和感觉刺激的丰富环境，有利于大脑发育和衰老。在环境中，已经考虑了从细胞和分子机制对神经形态和神经发生的宏观变化的多种反应，以证明环境输入可以调节大鼠生命各个阶段的大脑可塑性。来自我们实验室的数据表明，丰富的环境增加了海马神经生长因子（NGF）基因表达和蛋白质水平，这可能是环境诱导的神经可塑性的基础。由于神经营养因子对于神经发育和存活至关重要，因此它们很可能参与了丰富经验所导致的大脑后果。

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