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The enteric nervous system II: gastrointestinal functions.

机译:肠神经系统II:肠胃功能。

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摘要

The enteric nervous system is involved in most of the physiological and pathophysiological processes in the gastrointestinal tract. This Minireview is part two of three and describes the role of the enteric nervous system in gastrointestinal functions (motility, exocrine and endocrine secretions, blood flow, and immune processes) in health and some disease states. In this context, the functional importance of the enteric nervous system for food intake, the gall bladder, and pancreas will be addressed. In specific, dysmotility, diarrhoea, constipation, non-occlusive intestinal ischaemia (intestinal angina), inflammation, cholelithiasis, cholecystitis, postcholecystectomy syndrome, and pancreatitis can be treated with neuroactive pharmacological agents. For example, serotonin receptor type four agonists can be used for the treatment of constipation, while nitric oxide synthesis inhibitors can be employed for the treatment of intestinal angina.
机译:肠神经系统参与胃肠道的大多数生理和病理生理过程。这份小型回顾是三部分的第二部分,描述了健康和某些疾病状态下肠神经系统在胃肠功能(运动,外分泌和内分泌,血流和免疫过程)中的作用。在这种情况下,将解决肠道神经系统对于食物摄入,胆囊和胰腺的功能重要性。具体而言,可以用神经活性药理药物治疗运动障碍,腹泻,便秘,非阻塞性​​肠缺血(肠绞痛),炎症,胆石症,胆囊炎,胆囊切除术后综合征和胰腺炎。例如,5-羟色胺受体四型激动剂可用于治疗便秘,而一氧化氮合成抑制剂可用于治疗肠绞痛。

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