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首页> 外文期刊>Pharmacology, Biochemistry and Behavior >Plants used in Chinese and Indian traditional medicine for improvement of memory and cognitive function.
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Plants used in Chinese and Indian traditional medicine for improvement of memory and cognitive function.

机译：中国和印度传统医学中用于改善记忆力和认知功能的植物。

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摘要

In traditional practices of Ayurvedic and Chinese medicine, numerous plants have been used to treat cognitive disorders, including neurodegenerative diseases such as Alzheimer's disease (AD). An ethnopharmacological approach has provided leads to identifying potential new drugs from plant sources, including those for cognitive disorders. Many drugs currently available in Western medicine were originally isolated from plants, or are derived from templates of compounds isolated from plants. Some anticholinesterase (anti-ChE) alkaloids isolated from plants have been investigated for their potential in the treatment of AD, and are now in clinical use. Galantamine, isolated from several plants including Lycoris radiata Herb., which was used in traditional Chinese medicine (TCM), is licensed in the United Kingdom for the treatment of mild to moderate AD. Various other plant species have shown pharmacological activities relevant to the treatment of cognitive disorders, indicating potential for therapeutic usein disorders such as AD. This article reviews some of the plants and their active constituents that have been used in traditional Ayurvedic medicine and TCM for their reputed cognitive-enhancing or antiageing effects. Plants and their constituents with pharmacological activities that may be relevant for the treatment of cognitive disorders, including enhancement of cholinergic function in the central nervous system (CNS), anti-inflammatory and antioxidant activities, are discussed.
机译：在传统的印度草药疗法和中药疗法中，许多植物已被用于治疗认知障碍，包括神经退行性疾病，例如阿尔茨海默氏病（AD）。种族药理学方法已导致从植物来源（包括用于认知障碍的植物来源）中识别潜在的新药。目前在西药中可获得的许多药物最初是从植物中分离出来的，或者是从植物中分离出来的化合物的模板衍生出来的。从植物中分离出的某些抗胆碱酯酶（抗ChE）生物碱已被研究具有治疗AD的潜力，现已投入临床使用。加兰他敏从包括传统中药（TCM）的石蒜Lycoris radiata Herb。等植物中分离出来，在英国获得了用于治疗轻度至中度AD的许可。多种其他植物物种已显示出与认知障碍的治疗有关的药理活性，表明其在诸如AD等疾病中具有治疗用途的潜力。本文介绍了一些植物及其有效成分，这些植物及其有效成分已在传统的印度草药和中草药中发挥着重要的认知增强或抗衰老作用。讨论了具有药理活性可能与认知障碍治疗有关的植物及其成分，包括增强中枢神经系统（CNS）的胆碱能功能，抗炎和抗氧化活性。

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