• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Pharmacology, Biochemistry and Behavior >Improved cognitive function in postmenopausal women after 12 weeks of consumption of a soya extract containing isoflavones.
【24h】

Improved cognitive function in postmenopausal women after 12 weeks of consumption of a soya extract containing isoflavones.

机译：食用含有异黄酮的大豆提取物12周后，绝经后妇女的认知功能得到改善。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

We previously reported that a high soya diet improved memory and frontal lobe function in young volunteers, and since soya isoflavones are agonists at oestrogen receptors, they may improve these functions in postmenopausal women. Thirty-three postmenopausal women (50-65 years) not receiving conventional hormone replacement therapy (HRT) were randomly allocated in a double-blind parallel study to receive a soya supplement (60 mg total isoflavone equivalents/day) or placebo for 12 weeks. They received a battery of cognitive tests and completed analogue rating scales of mood and sleepiness, and a menopausal symptoms questionnaire before the start of treatment and then after 12 weeks of treatment. Those receiving the isoflavone supplement showed significantly greater improvements in recall of pictures and in a sustained attention task. The groups did not differ in their ability to learn rules, but the isoflavone supplement group showed significantly greater improvements in learning rule reversals. They also showed significantly greater improvement in a planning task. There was no effect of treatment on menopausal symptoms, self-ratings of mood, bodily symptoms or sleepiness. Thus, significant cognitive improvements in postmenopausal women can be gained from 12 weeks of consumption of a supplement containing soya isoflavones that are independent of any changes in menopausal symptoms, mood or sleepiness.
机译：我们以前曾报道过，高大豆饮食可以改善年轻志愿者的记忆力和额叶功能，并且由于大豆异黄酮是雌激素受体的激动剂，因此它们可能会改善绝经后妇女的这些功能。在一项双盲平行研究中，将33例未接受常规激素替代疗法（HRT）的绝经后妇女（50-65岁）随机分配至接受大豆补充剂（总异黄酮当量/天60毫克/天）或安慰剂，持续12周。他们在治疗开始前和治疗12周后接受了一系列认知测试，并完成了情绪和嗜睡的类似评分量表，还接受了更年期症状调查表。那些接受异黄酮补充剂的人在回忆图片和持续关注任务方面显示出明显更大的改善。各组学习规则的能力没有差异，但异黄酮补充剂组在逆转学习规则方面显示出明显更大的改善。他们还显示出计划任务方面的显着改善。治疗对更年期症状，情绪自评，身体症状或嗜睡无影响。因此，服用含有大豆异黄酮的补充剂，与绝经期症状，情绪或困倦的任何变化无关，服用绝经后12周即可使绝经后妇女的认知能力得到显着改善。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号