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Cocaine's effects on detection, discrimination, and identification of auditory stimuli by baboons.

机译:可卡因对狒狒对听觉刺激的检测,区分和识别的影响。

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The perceptual effects of cocaine were examined under conditions that required baboons to detect the presence of tones as well as to identify tones of different pitches, and the results compared to the results of prior studies on cocaine's effects on the detection of tones, the discrimination of different tone pitches, and the discrimination of different human vowel sounds of similar pitch. A reaction time procedure was employed in which baboons were trained to press a lever in the presence of a visual "ready" signal, and release the lever only when one tone pitch occurred, but not release the lever when a second, different tone pitch occurred. Changes in the percentage of correct detections and median reaction times for each tone were measured following intramuscular administration of cocaine (0.01-1.0 mg/kg). Cocaine impaired tone identification and shortened reaction times to the tones in all baboons. Cocaine's effects on accuracy, however, were primarily due to elevations in false alarm rates, as opposed to detection of the stimuli themselves. The results demonstrate that cocaine impairs the discriminability of tone pitches in baboons, and that such impairments can depend upon the type of stimuli employed (tones vs. speech sounds) and the type of procedure employed (discrimination vs. identification).
机译:在要求狒狒检测音调是否存在以及识别不同音调的条件下,对可卡因的感官效果进行了检查,并将该结果与先前关于可卡因对音调检测,歧视性的区分的研究结果进行了比较。不同的音调,以及对相似音调的不同人类元音的区分。采用了反应时间程序,其中训练狒狒在出现视觉“就绪”信号的情况下按下操纵杆,仅在出现一个音高时才释放操纵杆,而在发生另一个不同音高时不释放操纵杆。 。肌肉注射可卡因(0.01-1.0 mg / kg)后,测量每种音调的正确检测百分比和中位反应时间的变化。可卡因损害了所有狒狒的音调识别能力,并缩短了对音调的反应时间。可卡因对准确性的影响主要是由于误报率的升高,而不是刺激本身的检测。结果表明,可卡因损害了狒狒音调的可分辨性,并且这种损害取决于所使用的刺激类型(音与语音)和所采用的程序类型(歧视与识别)。

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