• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Pharmacology, Biochemistry and Behavior >Sexual-incentive motivation and paced sexual behavior in female rats after treatment with drugs modifying dopaminergic neurotransmission.
【24h】

Sexual-incentive motivation and paced sexual behavior in female rats after treatment with drugs modifying dopaminergic neurotransmission.

机译：用修饰多巴胺能神经传递的药物治疗后，雌性大鼠的性动机和性行为节奏加快。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The effects of the dopamine receptor agonist apomorphine, the dopamine releaser amphetamine, and the dopamine receptor antagonist cis(Z)-flupenthixol on sexual-incentive motivation and on paced-mating behavior were studied in female rats. Apomorphine, in the doses of 0.125 and 0.5 mg/kg, showed a tendency to reduce incentive motivation. Ambulatory activity was inhibited, evidenced both by diminished distance moved and reduced velocity of movement. Amphetamine (0.25 and 1 mg/kg) and flupenthixol (0.25 and 0.5 mg/kg) failed to modify incentive motivation while stimulating and reducing ambulatory activity, respectively. In the mating test, apomorphine enhanced the latency to enter the male's half and reduced the number of proceptive behaviors. However, these effects were associated with the appearance of stereotyped sniffing. Amphetamine increased the propensity to escape from the male after a mount without having other effects. Flupenthixol augmented the duration of the lordosis posture. Neither amphetamine nor flupenthixol affected sniffing. These data show that facilitated dopaminergic neurotransmission stimulates neither paced female sexual behavior nor sexual-incentive motivation. Dopamine receptor blockade has slight consequences. It is concluded that dopamine is not a transmitter of major importance for unconditioned female sexual motivation and behavior.
机译：在雌性大鼠中研究了多巴胺受体激动剂阿扑吗啡，多巴胺释放剂苯丙胺和多巴胺受体拮抗剂顺式（Z）-氟喷他醇对性动机和节律性交配行为的影响。阿朴吗啡的剂量为0.125和0.5 mg / kg，显示出降低激励动机的趋势。门诊活动受到抑制，既可以通过减小的移动距离又可以减小移动的速度来证明。苯丙胺（0.25和1 mg / kg）和氟喷他索（0.25和0.5 mg / kg）在刺激和减少非卧床活动时不能分别改变刺激动机。在交配试验中，阿扑吗啡增加了进入雄性一半的潜伏期，并减少了性行为的次数。然而，这些影响与刻板的嗅探的出现有关。苯丙胺增加了坐骑后从雄性身上逃脱的倾向，而没有其他影响。氟喷他索增加了脊柱前凸姿势的持续时间。苯丙胺和氟哌丁醇均不影响嗅觉。这些数据表明，促进的多巴胺能神经传递既不会刺激节奏的女性性行为，也不会刺激性动机。多巴胺受体阻滞有轻微后果。结论是，多巴胺对于无条件的女性性动机和行为并不是重要的传递者。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号