The effects of caffeine-induced arousal on global versus local object focus were investigated in non-habitual consumers using a double-blind, within-subjects, repeated-measures design. Following an overnight fast, low caffeine consumers (N=36; M=42.5mg/day caffeine) completed 5 counterbalanced test sessions (normal consumption, 0mg, 100mg, 200mg, and 400mg) separated by at least 3 days. During each session, volunteers either consumed their normal amount of caffeine or were administered 1 of 4 treatment pills. One hour later they completed two tasks assessing visual attention, in counterbalanced order. Measures of mood, salivary caffeine and cortisol were taken at multiple time points. Dose-dependent elevation of caffeine in the saliva demonstrated the experimental manipulation was effective. Furthermore, analyses of the mood and arousal measures detected consistent changes on arousal subscales and caffeine administration elevated saliva cortisol. Analyses of the visual attention tasks revealed that caffeine-induced physiological arousal produced global processing biases, after as little as 100mg caffeine. These data suggest caffeine consumption may influence how individuals attend to and process information in their environment and could influence daily tasks such as face recognition, learning new environments and navigation, especially for those who normally consume little caffeine.
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机译：使用双盲，受试者内部，重复测量设计，在非习惯性消费者中研究了咖啡因诱发的唤醒对整体和局部物体聚焦的影响。隔夜禁食后，低咖啡因的消费者（N = 36; M = 42.5mg /天的咖啡因）完成了至少3天的5个平衡测试阶段（正常消费，0mg，100mg，200mg和400mg）。在每个疗程中，志愿者要么食用了正常量的咖啡因，要么服用了4种治疗药中的1种。一小时后，他们以平衡的顺序完成了两项评估视觉注意力的任务。在多个时间点进行情绪，唾液咖啡因和皮质醇的测量。唾液中咖啡因的剂量依赖性升高表明实验操作是有效的。此外，对情绪和唤醒措施的分析发现，唤醒分量表上的变化一致，咖啡因给药后唾液皮质醇水平升高。对视觉注意任务的分析显示，咖啡因诱导的生理唤醒在仅摄取100毫克咖啡因后就产生了整体加工偏差。这些数据表明，咖啡因的摄入可能会影响个人在环境中参与和处理信息的方式，并可能影响日常任务，例如面部识别，学习新环境和导航，尤其是对于那些通常很少摄入咖啡因的人。
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