• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Pharmacology, Biochemistry and Behavior >Prolonged treatment with vitamins C and E separately and together decreases anxiety-related open-field behavior and acoustic startle in hooded rats.
【24h】

Prolonged treatment with vitamins C and E separately and together decreases anxiety-related open-field behavior and acoustic startle in hooded rats.

机译：长期单独使用维生素C和E共同治疗可降低蒙面大鼠焦虑相关的开放视野行为和听觉惊吓。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Adult male and female hooded rats (about 110 days old) consumed vitamins C and E separately and combined together in their drinking water and were assessed for anxiety approximately 50 and then 80 days later in an open field and an acoustic startle apparatus. They were tested when 160+ days old, and then again at 190+ days. For both testing ages combined, the vitamins and their combination increased open-field ambulation and occupancy of the four center squares of the apparatus, while also accordingly decreasing occupancy of the four corners. Treatment with vitamins C and E separately and combined together also decreased acoustic startle amplitude. While there were several significant overall sex and testing age differences, there was no evidence that the vitamin treatment effects were dependent on the operation of either variable. There was also no evidence of synergism between vitamins C and E in their effects. It was suggested that decreases in anxiety produced by the vitamins may have arisen from their antioxidant properties, attenuation of cortisol activity or some as yet undetermined effects on anxiety-related brain structures and neurotransmitters.
机译：成年雄性和雌性连帽大鼠（约110天大）分别摄入维生素C和E，并在其饮用水中混合在一起，大约50天后，然后在80天后在声场惊吓仪中评估焦虑。他们在160天以上时进行了测试，然后在190天以上时进行了测试。对于两个测试年龄的组合，维生素及其组合增加了器械四个中心方格的开阔运动和占用，同时也相应减少了四个角的占用。分别使用维生素C和E并结合在一起进行治疗也降低了听觉惊吓的幅度。尽管总体性别和测试年龄存在显着差异，但没有证据表明维生素治疗效果取决于这两个变量的作用。也没有证据表明维生素C和E之间的协同作用。有人提出，维生素产生的焦虑症的减轻可能是由于其抗氧化特性，皮质醇活性的减弱或对与焦虑有关的大脑结构和神经递质的某些尚未确定的影响。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号