Novel glutamatergic agents for major depressive disorder and bipolar disorder

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Novel glutamatergic agents for major depressive disorder and bipolar disorder

机译：适用于重度抑郁症和双相情感障碍的新型谷氨酸能药物

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Mood disorders such as major depressive disorder (MDD) and bipolar disorder (BPD) are common, chronic, recurrent mental illnesses that affect the lives and functioning of millions of individuals worldwide. Growing evidence suggests that the glutamatergic system is central to the neurobiology and treatment of these disorders. Here, we review data supporting the involvement of the glutamatergic system in the pathophysiology of mood disorders as well as the efficacy of glutamatergic agents as novel therapeutics.

机译：情绪障碍，例如重度抑郁症（MDD）和躁郁症（BPD），是常见，慢性，复发性精神疾病，会影响全球数百万个人的生活和功能。越来越多的证据表明，谷氨酸能系统对于这些疾病的神经生物学和治疗至关重要。在这里，我们审查数据支持谷氨酸能系统参与情绪障碍的病理生理以及谷氨酸能药物作为新型疗法的功效。

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《Pharmacology, Biochemistry and Behavior》 |2012年第4期|共10页
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正文语种 eng
中图分类药理学;
关键词
Bipolar disorder; Depression; Glutamate; Mood disorders; Novel treatments; Pathophysiology;

机译：躁郁症;抑郁症;谷氨酸;情绪障碍;新颖治疗;病理生理学;

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1. Novel glutamatergic agents for major depressive disorder and bipolar disorder [J] . Pharmacology, Biochemistry and Behavior . 2012,第4期

机译：适用于重度抑郁症和双相情感障碍的新型谷氨酸能药物
2. Add-on high frequency deep transcranial magnetic stimulation (dTMS) to bilateral prefrontal cortex in depressive episodes of patients with major depressive disorder, bipolar disorder I, and major depressive with alcohol use disorders [J] . Rapinesi Chiara, Kotzalidis Georgios D., Ferracuti Stefano, Neuroscience Letters: An International Multidisciplinary Journal Devoted to the Rapid Publication of Basic Research in the Brain Sciences . 2018,第期

机译：在主要抑郁症，双相情感障碍患者的抑郁发作中的双侧前额外皮层的加载高频深颅磁刺激（DTMS），双相障碍症和酒精使用障碍的重大抑郁症
3. Comparing the Phenomenology of Depressive Episodes in Bipolar I and II Disorder and Major Depressive Disorder Within Bipolar Disorder Pedigrees [J] . Adam Wright, Andrew Frankland, Colleen K. Loo, Primary care companion to the journal of clinical psychiatry . 2015,第1期

机译：比较双相I型和II型双相情感障碍和双相情感障碍谱系内的主要抑郁障碍的抑郁发作的现象学
4. Predictors for Switch from Unipolar Major Depressive Disorder to Bipolar Disorder: Applying Classification and Regression Trees Method to the Taiwan National Health Insurance Database [C] . Cheng-Che Shen, Ya-Han Hu, I-Chiu Chang International conference on smart health . 2017

机译：从单相严重抑郁症转换为双相情感障碍的预测因子：将分类和回归树方法应用于台湾国民健康保险数据库
5. Genetic Biomarkers of Psychiatric Disease: Discriminating Bipolar Disorder from Major Depressive Disorder with Polygenic Risk Scores [D] . ?Liebers, David T. 2020

机译：精神疾病的遗传生物标志物：鉴别多种抑郁症与多种子基风险评分的双相情感障碍
6. Novel glutamatergic agents for major depressive disorder and bipolar disorder [O] . Rodrigo Machado-Vieira, Lobna Ibrahim, Ioline D. Henter, -1

机译：重大抑郁症和双相障碍的新型谷氨酸剂
7. Novel glutamatergic agents for major depressive disorder and bipolar disorder [O] . Rodrigo Machado-Vieira, Lobna Ibrahim, Ioline D. Henter, 2012

机译：重大抑郁症和双相障碍的新型谷氨酸剂

Novel glutamatergic agents for major depressive disorder and bipolar disorder

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