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Bioactivity from Toona ciliata Stem Bark

机译:香椿茎皮的生物活性

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Studies were carried out to screen Toona ciliata M. J. Roemer (Meliaceae) for its cytotoxicity and antitumor activity. The crude extracts and a major isolate, siderin, obtained from the petroleum ether extract of T. ciliata were found to exhibit significant cytotoxicity in the brine shrimp lethality bioassay. In the potato disc bioassay, the extracts and the fractions demonstrated mild to moderate antitumor activity. The results were compared with those produced by vincristine sulphate.
机译:进行了研究以筛选Toona ciliata M. J. Roemer(M科)的细胞毒性和抗肿瘤活性。从纤毛虫的石油醚提取物中获得的粗提物和主要分离物铁蛋白,在盐水虾致死性生物测定中被发现具有明显的细胞毒性。在马铃薯圆盘生物测定中,提取物和级分显示出轻至中度的抗肿瘤活性。将结果与硫酸长春新碱产生的结果进行比较。

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