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首页> 外文期刊>Physics in medicine and biology. >Dosimetric validation of the Acuros XB Advanced Dose Calculation algorithm: fundamental characterization in water.
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Dosimetric validation of the Acuros XB Advanced Dose Calculation algorithm: fundamental characterization in water.

机译：Acuros XB高级剂量计算算法的剂量学验证：水中的基本表征。

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A new algorithm, Acuros(R) XB Advanced Dose Calculation, has been introduced by Varian Medical Systems in the Eclipse planning system for photon dose calculation in external radiotherapy. Acuros XB is based on the solution of the linear Boltzmann transport equation (LBTE). The LBTE describes the macroscopic behaviour of radiation particles as they travel through and interact with matter. The implementation of Acuros XB in Eclipse has not been assessed; therefore, it is necessary to perform these pre-clinical validation tests to determine its accuracy. This paper summarizes the results of comparisons of Acuros XB calculations against measurements and calculations performed with a previously validated dose calculation algorithm, the Anisotropic Analytical Algorithm (AAA). The tasks addressed in this paper are limited to the fundamental characterization of Acuros XB in water for simple geometries. Validation was carried out for four different beams: 6 and 15 MV beams from a Varian Clinac 2100 iX, and 6 and 10 MV 'flattening filter free' (FFF) beams from a TrueBeam linear accelerator. The TrueBeam FFF are new beams recently introduced in clinical practice on general purpose linear accelerators and have not been previously reported on. Results indicate that Acuros XB accurately reproduces measured and calculated (with AAA) data and only small deviations were observed for all the investigated quantities. In general, the overall degree of accuracy for Acuros XB in simple geometries can be stated to be within 1% for open beams and within 2% for mechanical wedges. The basic validation of the Acuros XB algorithm was therefore considered satisfactory for both conventional photon beams as well as for FFF beams of new generation linacs such as the Varian TrueBeam.
机译：Varian Medical Systems在Eclipse规划系统中引入了一种新算法Acuros®XB Advanced Dose Calculation，用于外部放射治疗中的光子剂量计算。 Acuros XB基于线性玻尔兹曼输运方程（LBTE）的解。 LBTE描述了辐射粒子穿过物质并与物质相互作用时的宏观行为。尚未评估Eclipse中Acuros XB的实现;因此，有必要执行这些临床前验证测试以确定其准确性。本文总结了Acuros XB计算与使用预先验证的剂量计算算法（各向异性分析算法（AAA））执行的测量和计算结果的比较结果。本文讨论的任务仅限于简单几何形状的水中Acuros XB的基本表征。对四种不同的光束进行了验证：来自Varian Clinac 2100 iX的6和15 MV光束，以及来自TrueBeam线性加速器的6和10 MV“无平坦滤波器”（FFF）光束。 TrueBeam FFF是在临床实践中最近在通用线性加速器上引入的新光束，以前尚未见过报道。结果表明，Acuros XB准确地再现了测量和计算（使用AAA）的数据，并且对于所有调查量仅观察到很小的偏差。通常，对于简单的几何形状，Acuros XB的总体精度可以说在开放式梁的1％以内，在机械楔形的2％以内。因此，对于常规光子束以及新一代直线加速器的FFF束（例如Varian TrueBeam），Acuros XB算法的基本验证被认为是令人满意的。

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