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首页> 外文期刊>Physics in medicine and biology. >An integrated bioimpedance - ECG gating technique for respiratory and cardiac motion compensation in cardiac PET
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An integrated bioimpedance - ECG gating technique for respiratory and cardiac motion compensation in cardiac PET

机译：集成的生物阻抗-ECG门控技术可用于心脏PET中的呼吸和心脏运动补偿

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摘要

Respiratory motion may degrade image quality in cardiac PET imaging. Since cardiac PET studies often involve cardiac gating by ECG, a separate respiratory monitoring system is required increasing the logistic complexity of the examination, in case respiratory gating is also needed. Thus, we investigated the simultaneous acquisition of both respiratory and cardiac gating signals using II limb lead mimicking electrode configuration during cardiac PET scans of 11 patients. In addition to conventional static and ECG-gated images, bioimpedance technique was utilized to generate respiratory- and dual-gated images. The ability of the bioimpedance technique to monitor intrathoracic respiratory motion was assessed estimating cardiac displacement between end-inspiration and -expiration. The relevance of dual gating was evaluated in left ventricular volume and myocardial wall thickness measurements. An average 7.6 ± 3.3mm respiratory motion was observed in the study population. Dual gating showed a small but significant increase (4ml, p = 0.042) in left ventricular myocardial volume compared to plain cardiac gating. In addition, a thinner myocardial wall was observed in dual-gated images (9.3 ± 1.3mm) compared to cardiac-gated images (11.3 ± 1.3mm, p = 0.003). This study shows the feasibility of bioimpedance measurements for dual gating in a clinical setting. The method enables simultaneous acquisition of respiratory and cardiac gating signals using a single device with standard ECG electrodes.
机译：呼吸运动可能会降低心脏PET成像中的图像质量。由于心脏PET研究通常涉及通过ECG进行心脏门控，因此，如果还需要进行呼吸门控，则需要单独的呼吸监测系统，从而增加检查的后勤复杂性。因此，我们调查了在11位患者的心脏PET扫描过程中使用II肢体铅模拟电极配置同时获取呼吸和心脏门控信号的情况。除了常规的静态和ECG门控图像外，还使用了生物阻抗技术来生成呼吸门控和双门控图像。评估了生物阻抗技术监测胸腔内呼吸运动的能力，以估计最终吸气和呼气之间的心脏位移。在左心室容积和心肌壁厚度测量中评估双重门控的相关性。在研究人群中平均观察到7.6±3.3mm的呼吸运动。与普通心脏门控相比，双重门控显示左心室心肌体积小而显着增加（4ml，p = 0.042）。此外，与心脏门控图像（11.3±1.3mm，p = 0.003）相比，双门控图像（9.3±1.3mm）观察到的心肌壁更薄。这项研究显示了在临床环境中双门控生物阻抗测量的可行性。该方法能够使用带有标准ECG电极的单个设备同时采集呼吸和心脏门控信号。

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