...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Physics in medicine and biology. >CTC-ask: a new algorithm for conversion of CT numbers to tissue parameters for Monte Carlo dose calculations applying DICOM RS knowledge.
【24h】

CTC-ask: a new algorithm for conversion of CT numbers to tissue parameters for Monte Carlo dose calculations applying DICOM RS knowledge.

机译：CTC-ask：一种利用DICOM RS知识将CT数转换为组织参数以进行蒙特卡洛剂量计算的新算法。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

One of the building blocks in Monte Carlo (MC) treatment planning is to convert patient CT data to MC compatible phantoms, consisting of density and media matrices. The resulting dose distribution is highly influenced by the accuracy of the conversion. Two major contributing factors are precise conversion of CT number to density and proper differentiation between air and lung. Existing tools do not address this issue specifically. Moreover, their density conversion may depend on the number of media used. Differentiation between air and lung is an important task in MC treatment planning and misassignment may lead to local dose errors on the order of 10%. A novel algorithm, CTC-ask, is presented in this study. It enables locally confined constraints for the media assignment and is independent of the number of media used for the conversion of CT number to density. MC compatible phantoms were generated for two clinical cases using a CT-conversion scheme implemented in both CTC-ask and the DICOM-RT toolbox. Full MC dose calculation was subsequently conducted and the resulting dose distributions were compared. The DICOM-RT toolbox inaccurately assigned lung in 9.9% and 12.2% of the voxels located outside of the lungs for the two cases studied, respectively. This was completely avoided by CTC-ask. CTC-ask is able to reduce anatomically irrational media assignment. The CTC-ask source code can be made available upon request to the authors.
机译：蒙特卡洛（MC）治疗计划的组成部分之一是将患者的CT数据转换为MC兼容的体模，该体模由密度和介质矩阵组成。最终的剂量分布在很大程度上受转换精度的影响。两个主要的影响因素是CT数到密度的精确转换以及空气和肺之间的适当区分。现有工具不能专门解决此问题。此外，它们的密度转换可能取决于所用介质的数量。空气和肺部的区别是MC治疗计划中的重要任务，分配不当可能导致局部剂量误差约10％。这项研究提出了一种新颖的算法CTC-ask。它允许对介质分配进行局部限制，并且与用于将CT数转换为密度的介质数无关。使用在CTC-ask和DICOM-RT工具箱中均实现的CT转换方案，为两个临床病例生成了MC兼容体模。随后进行完整的MC剂量计算，并比较所得的剂量分布。对于这两个案例，DICOM-RT工具箱分别错误地分配了位于肺外部的9.9％和12.2％的体素。 CTC-ask完全避免了这种情况。要求CTC可以减少解剖学上不合理的介质分配。可以根据要求向作者提供CTC询问源代码。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号