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首页> 外文期刊>Physics in medicine and biology. >Brain tumor imaging using small-angle x-ray scattering tomography.
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Brain tumor imaging using small-angle x-ray scattering tomography.

机译:脑肿瘤成像使用小角度X射线散射断层扫描。

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摘要

We demonstrate high-resolution small-angle x-ray scattering computed tomography (SAXS-CT) of soft matter and soft tissue samples. Complete SAXS patterns over extended ranges of momentum transfer are reconstructed spatially resolved from volumes inside an extended sample. Several SAXS standard samples are used to quantitatively validate the method and demonstrate its performance. Further results on biomedical tissue samples (rat brains) are presented that demonstrate the advantages of the method compared to existing biomedical x-ray imaging approaches. Functional areas of the brains as well as tumor morphology are imaged. By providing insights into the structural organization at the nano-level, SAXS-CT complements and extends results obtainable with standard methods such as x-ray absorption tomography and histology.
机译:我们演示了高分辨率的软物质和软组织样品的小角度X射线散射计算机断层扫描(SAXS-CT)。从动量传递的扩展范围内的完整SAXS模式可以从扩展样本内的空间进行空间解析。几个SAXS标准样品用于定量验证该方法并证明其性能。提出了关于生物医学组织样本(大鼠大脑)的进一步结果,这些结果证明了该方法与现有生物医学X射线成像方法相比的优势。对大脑的功能区域以及肿瘤形态进行成像。通过提供有关纳米级结构组织的见解,SAXS-CT补充并扩展了可通过标准方法(例如X射线吸收层析成像和组织学)获得的结果。

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