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A method for high-energy, low-dose mammography using edge illumination x-ray phase-contrast imaging

机译:一种使用边缘照明x射线相衬成像的高能,低剂量乳腺摄影方法

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摘要

Since the breast is one of the most radiosensitive organs, mammography is arguably the area where lowering radiation dose is of the uttermost importance. Phase-based x-ray imaging methods can provide opportunities in this sense, since they do not require x-rays to be stopped in tissue for image contrast to be generated. Therefore, x-ray energy can be considerably increased compared to those usually exploited by conventional mammography. In this article we show how a novel, optimized approach can lead to considerable dose reductions. This was achieved by matching the edge-illumination phase method, which reaches very high angular sensitivity also at high x-ray energies, to an appropriate image processing algorithm and to a virtually noise-free detection technology capable of reaching almost 100% efficiency at the same energies. Importantly, while proof-of-concept was obtained at a synchrotron, the method has potential for a translation to conventional sources.
机译:由于乳房是对放射线最敏感的器官之一,因此乳房X线照相术可以说是降低放射线剂量至关重要的区域。基于相位的X射线成像方法可以提供这种意义上的机会,因为它们不需要将X射线停在组织中以生成图像对比度。因此,与常规乳腺X线摄影通常所利用的能量相比,X射线能量可以大大增加。在本文中,我们展示了一种新颖,优化的方法如何导致可观的剂量减少。这是通过将边缘照明相位方法(在高X射线能量下也达到非常高的角灵敏度)与合适的图像处理算法和几乎无噪声的检测技术相匹配而实现的,该检测技术能够在高X射线能量下达到近100%的效率。相同的能量。重要的是,虽然在同步加速器中获得了概念证明,但该方法具有转化为常规信号源的潜力。

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