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首页> 外文期刊>Pharmacological research: The official journal of The Italian Pharmacological Society >Lippia alba, Melissa officinalis and Cymbopogon citratus: effects of the aqueous extracts on the isolated hearts of rats.
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Lippia alba, Melissa officinalis and Cymbopogon citratus: effects of the aqueous extracts on the isolated hearts of rats.

机译：Lippia alba，Melissa officinalis和Cymbopogon citratus：水提物对大鼠离体心脏的影响。

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摘要

This research was developed to evaluate the actions of the aqueous extracts of leaves of Lippia alba, Melissa officinalis and Cymbopogon citratus upon contractile force (CF) and cardiac rate (CR). For the experiments in isolated heart, 21 male adult rats were used. The hearts were perfused according to Langendorff's method. The records of CF and CR were obtained in control and after application of the extracts. The extracts were utilized in doses: 0.038, 0.38, 3.8 and 38mg. Results obtained were compared by statistic analyses. The aqueous extracts provoked significant CR reduction and did not alter the CF. The negative CR effect may have occurred by cardiac muscarinics receptors stimulation.
机译：这项研究的目的是评估白头翁，蜜蜂花和柠檬柠条的水提取物对收缩力（CF）和心率（CR）的作用。对于离体心脏实验，使用了21只雄性成年大鼠。根据Langendorff的方法对心脏进行灌注。 CF和CR的记录是在对照和提取物施用后获得的。提取物的使用剂量为：0.038、0.38、3.8和38mg。通过统计分析比较获得的结果。水提取物引起显着的CR降低，并且不改变CF。心脏毒蕈碱受体刺激可能导致CR阴性。

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