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Clinical application of the P300 event-related brain potential.

机译:P300事件相关脑潜能的临床应用。

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The P300 brain potential can provide information about cognition that is quantitatively comparable to other clinically used biomedical assays. Causes of P300 variability with respect to task and biologic determinants have been well characterized so that refinement of ERP methods for clinical applications is possible. Elaboration of how P300 and other ERP components reflect neuropsychologic processes would help to increase their clinical relevance. In particular, development of reliable P3a paradigms used in conjunction with P3b tasks promises to augment dramatically the applicability and sensitivity of ERPs. Use of P300 as a clinical evaluation tool should be revisited with contemporary theory, methods, and analysis procedures because a reliable neuroelectric measure of mental function would redefine the assessment of cognitive disorders.
机译:P300的大脑潜能可以提供与认知有关的信息,这些信息在数量上可与其他临床使用的生物医学测定相比。关于任务和生物学决定因素的P300变异性的原因已得到很好的表征,因此可以改进临床应用中的ERP方法。详细说明P300和其他ERP组件如何反映神经心理学过程将有助于增加它们的临床相关性。特别是,与P3b任务结合使用的可靠P3a范例的开发有望大大提高ERP的适用性和敏感性。应将P300用作临床评估工具,应从当代的理论,方法和分析程序中重新审视,因为可靠的神经功能神经电测量将重新定义认知障碍的评估。

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