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首页> 外文期刊>Physica, A. Statistical mechanics and its applications >Breathing of voltage dependent anion channel as revealed by the fractal property of its gating
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Breathing of voltage dependent anion channel as revealed by the fractal property of its gating

机译：通过门控的分形特性揭示了电压依赖性阴离子通道的呼吸

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摘要

The gating of voltage dependent anion channel (VDAC) depends on the movement of voltage sensors in the transmembrane region, but the actual mechanism is still not well understood. With a view to understand the phenomenon we have analyzed the current recordings of VDAC in lipid bilayer membrane (BLM) and found that the data show self-similarity and fractal characteristics. We look for the microscopic and molecular basis of fractal behavior of gating of VDAC. A model describing the oscillatory dynamics of voltage sensors of VDAC in the transmembrane region under applied potential has been proposed which gives rise to the aforesaid fractal behavior. (c) 2007 Published by Elsevier B.V.
机译：电压依赖性阴离子通道（VDAC）的门控取决于跨膜区域中电压传感器的运动，但实际的机制仍未很好理解。为了了解这种现象，我们分析了脂质双层膜（BLM）中VDAC的当前记录，发现数据显示出自相似性和分形特征。我们寻找VDAC门控分形行为的微观和分子基础。提出了描述施加电压下跨膜区域中VDAC的电压传感器的振荡动力学的模型，该模型引起了上述的分形行为。 （c）2007年由Elsevier B.V.

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