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SERS INVESTIGATION OF PARACETAMOL ADSORBEDON Ag ISLAND FIIMS

机译:草甘膦ADSORBEDON Ag ISLAND FIIMS的SERS调查

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Commercial paracetamol drugs (normal and sinus) are analyzed using Raman and SERS spectroscopies. The active compound present in commercially tablets could be accurately identified and monitored even through the blister pack. Raman spectra show that the normal paracetamol contains a mixture between the monoclinic and orthorhombic forms, while the sinus paracetamol contains just the monoclinic form. The SERS spectra of paracetamol on Ag island films of different roughnesses have been obtained and discussed. From the SERS spectra it was concluded that the paracetamol molecules are chemisorbed on the Ag-surface in a flat orientation through the lone pair electrons of the nitrogen atom and the π electrons of the aromatic ring.
机译:使用拉曼光谱和SERS光谱分析市售扑热息痛药物(正常和鼻窦)。即使通过泡罩包装,也可以准确鉴定和监测市售片剂中存在的活性化合物。拉曼光谱显示,正常扑热息痛包含单斜晶型和正交晶型之间的混合物,而鼻窦扑热息痛仅包含单斜晶型形式。得到并讨论了对乙酰氨基酚在不同粗糙度的银岛薄膜上的SERS光谱。从SERS光谱得出结论,对乙酰氨基酚分子通过氮原子的孤对电子和芳环的π电子以平坦的取向化学吸附在Ag表面上。

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