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首页> 美国政府科技报告 >Multidiscipline Approach to Understanding of Traumatic Brain Injury and theEvaluation of Drugs to Enhance Neurological Recovery after Traumatic Brain Injury
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Multidiscipline Approach to Understanding of Traumatic Brain Injury and theEvaluation of Drugs to Enhance Neurological Recovery after Traumatic Brain Injury

机译：创伤性脑损伤后多学科探讨创伤性脑损伤及药物评价促进神经功能恢复

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In combat, head wounds account for almost half of all single wound deaths. SinceWorld War II neurosurgical mortality has approximated 10%, indicating no overall improvement in the lethality of brain wounds incurred in combat (1) In an attempt to alleviate this problem the US Army Medical Research and Development Command sponsored a project to develop an experimental model of brain wounding so that better treatments for brain wounded soldiers could be developed. This project was halted by animal zealots (2). The present brain injury project being conducted at Louisiana State University Medical Center is an attempt to continue the U.S. Army's efforts to develop better treatments for brain injury. In this new effort we modeled brain injury in the anesthetized rat by impacting the right sensorimotor area with a pneumatically driven piston. Owing in no small measure to the animal activists, most brain trauma work around the world is now done in the anesthetized rat using fluid percussion, weight drop or a piston impact.

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