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首页> 美国政府科技报告 >Effect of High-Dose Dexamethasone on the Outcome of Acute Encephalitis Due to Japanese Encephalitis Virus. (Reannouncement with New Availability Information).
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Effect of High-Dose Dexamethasone on the Outcome of Acute Encephalitis Due to Japanese Encephalitis Virus. (Reannouncement with New Availability Information).

机译：大剂量地塞米松对流行性乙型脑炎病毒致急性脑炎结局的影响。 （重新公布新的可用性信息）。

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Death due to Japanese encephalitis (JE) usually occurs in the first 5 days of hospitalization as a result of deepening coma with respiratory arrest. Death May result from edema induced increases in intracranial pressure which might be reduced by the administration Of steroids. Sixty-five patients presenting to 4 Thai hospitals with a diagnosis Of acute JE were randomized in a double masked fashion, stratified by initial mental status into a placebo group (saline) or a treatment group (Dexamethasone 0.6 mg/kg intravenously as a loading dose followed by .2 mg/kg (24% treatment group, 27% control group), days to alert mental included mortality virus or JE specific IgM antibody. Important Outcome measures status (3.9 versus every 6 hours for 5 days). Fifty-five of 65 patients had JE confirmed by detection of 6.2) and neurological status 3 months after discharge (45 % abnormal in each group). No statistically significant benefit could be detected. UNCLASS, ENCEPHALITIS, JAPANESE ENCEPHALITIS (JE) DEXAMETHASONE.

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