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Activity of a NAAG-Hydrolyzing Enzyme in Brain May Affect Seizure Susceptibilityin Genetically Epilepsy-Prone Rats

机译：脑内NaaG水解酶的活性可能影响遗传性癫痫发作大鼠的癫痫发作易感性

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N-acetyl-aspartyl-glutamate (NAAG) is a dipeptide endogenous to the brain,localized in neurons, releasable from brain tissue, associated with excitatory effects when applied to neurons and elicits seizures with intrahippocampal injection. We previously reported that kindled seizures increased NAAG levels in

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Meyerhoff, J. L.;
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年度 1992
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总页数 11
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Brain; Epilepsy; Enzymes; Injection; Membranes(Biology); Nerve cells; Neurobiology; Peptide hydrolases; Rats; Reprints; Central nervous system; Amino acids; Functions; Cerebellum; Control; Neurotransmitters; Synapse; Hippocampus;

机译：脑;癫痫;酶;注射;膜（生物学）;神经细胞;神经生物学;肽水解酶;大鼠;重印;中枢神经系统;氨基酸;功能;小脑;对照;神经递质;突触;海马;

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1. Alterations in mRNA expression of systems that regulate neurotransmitter synaptic content in seizure-naive genetically epilepsy-prone rat (GEPR): transporter proteins and rate-limiting synthesizing enzymes for norepinephrine, dopamine and serotonin. [J] . Szot P, Reigel CE, White SS, Brain research. Molecular brain research . 1996,第1a2期

机译：调节天真的癫痫易发大鼠（GEPR）中神经递质突触含量的系统的mRNA表达变化：去甲肾上腺素，多巴胺和5-羟色胺的转运蛋白和限速合成酶。
2. Regional Expression of Multidrug Resistance Genes in Genetically Epilepsy-prone Rat Brain after a Single Audiogenic Seizure. [J] . Kwan P, Sills GJ, Butler E, Epilepsia: Journal of the International League against Epilepsy . 2002,第11期

机译：单一音源性癫痫发作后，遗传易发性癫痫大鼠脑中多药抗性基因的区域表达。
3. The use of neural transplantation for suppression of seizure activity in genetically epilepsy-prone rats. [J] . Ermakova IV, Kuznetsova GD, Loseva EV, Bulletin of experimental biology and medicine . 2000,第9期

机译：神经移植在遗传易发性癫痫大鼠中抑制癫痫发作活动的用途。
4. Effects of L-Glutamic Acid, Gamma-Aminobutiric Acid and Kainic Acid on the Surface Electrical Charge and Enzyme Activity of Rat Brain Synaptosomes [C] . V. Doltchinkova, M. Shkodrova, N. Mouleshkova, Jubilee International Conference of the Balkan Physical Union . 2019

机译：L-谷氨酸，γ-氨基磺酸和KAINIC酸对大鼠脑突触素表面电荷和酶活性的影响
5. In vitro electrophysiological properties of inferior colliculus cortex neurons in genetically epilepsy-prone rats and rats undergoing ethanol withdrawal. [D] . Li, Yang. 1997

机译：遗传易发性癫痫大鼠和接受乙醇戒断的大鼠下丘脑皮层神经元的体外电生理特性。
6. Effects of Intraventricular Locus Coeruleus Transplants on Seizure Severity in Genetically Epilepsy-Prone Rats Following Depletion of Brain Norepinephrine [O] . R. W. Clough, R. A. Browning, M. L. Maring, 1994

机译：脑室蓝斑移植对脑去甲肾上腺素耗竭后遗传性癫痫发作大鼠癫痫发作严重程度的影响
7. Effects of Intraventricular Locus Coeruleus Transplants on Seizure Severity in Genetically Epilepsy-Prone Rats Following Depletion of Brain Norepinephrine [O] . Clough, R. W., Browning, R. A., Maring, M. L., 1994

机译：脑室蓝斑小脑移植对脑去甲肾上腺素耗竭后遗传性癫痫发作大鼠癫痫发作严重程度的影响

Activity of a NAAG-Hydrolyzing Enzyme in Brain May Affect Seizure Susceptibilityin Genetically Epilepsy-Prone Rats

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