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Can Post mTBI Neurological Soft Signs Predict Postconcussive and PTSD Symptoms: A Pilot Study

机译:可以发布mTBI神经系统软指征预测脑震荡和创伤后应激障碍的症状:一项试点研究

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Neurological soft signs (NSS) are subtle indicators of brain dysfunction. NSS have been found to be elevated in a variety of mental disorders, including post-traumatic stress disorder (PTSD), but they have scarcely been studied in TBI. The present study in progress measured NSS in the acute aftermath of a mTBI and evaluated their ability to predict subsequent postconcussive symptoms. We have finished all study recruitment and enrollment to date. Only data analysis remains. We screened 99 subjects via the Massachusetts General Hospital Emergency Department leading to 21 viable subjects that were enrolled, three of whom were subsequently excluded for not meeting eligibility criteria. One additional subject was lost to follow-up after completion of the first visit. The remaining 17 enrolled subjects have successfully completed the full three-month protocol. The video-recorded data for 15 subjects was encrypted and analyzed by our off site consultant, Dr. Gurvits, the originator of the NSS battery in current use. The remaining 2 subjects data await analysis. Preliminary data analyses have been performed.

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