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Immunodominant Antigenic Sites in Primate Immunodeficiency Viruses and In vivoProtection

机译：灵长类动物免疫缺陷病毒和体内保护中的免疫显性抗原位点

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A vaccine against infection or immunosuppressive disease by primate lentiviruseshas to overcome three factors critical for viral pathogenesis: (1) the capacity of the virus to persist, (2) the progressive destruction of humoral as well as cell-mediated immune functions, and (3) the variability of the envelope proteins. We have addressed these problems by searching for neutralizing epitopes and by developing a useful animal model. In this work it is assumed by inference that neutralizing antibodies may play an essential role in restricting virus replication.

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作者
Norrby, E.; Putkonen, P.; Albert, J.; Fenyoe, E. M.;
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年度 1991
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总页数 10
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Human immunodeficiency viruses; Antigens; Vaccines; Immunosuppression; In vivoanalysis; Reprints;

机译：人类免疫缺陷病毒;抗原;疫苗;免疫抑制;体内分析;重印;

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专利

1. Modulation of immunodominant sites in influenza hemagglutinin compromise antigenic variation and select receptor-binding variant viruses. [J] . F Temoltzin-Palacios, D B Thomas The Journal of Experomental Medicine . 1994,第5期

机译：流感血凝素中免疫优势位点的调节会损害抗原变异并选择受体结合变异病毒。
2. Modulation of immunodominant sites in influenza hemagglutinin compromise antigenic variation and select receptor-binding variant viruses. [J] . F Temoltzin-Palacios, D B Thomas The Journal of Experomental Medicine . 1994,第5期

机译：流感血凝素中免疫优势位点的调节会损害抗原变异并选择受体结合变异病毒。
3. Molecular methods for evaluation of virological status of nonhuman primates challenged with simian immunodeficiency or simian-human immunodeficiency viruses. [J] . Lee E. M., Chung H. K., Livesay J., Journal of Virological Methods . 2010,第2期

机译：评估猿猴免疫缺陷病毒或猿猴-人类免疫缺陷病毒攻击的非人类灵长类动物的病毒学状态的分子方法。
4. Ag85 homologues from culture filtrate of Mycobacterium avium subsp. paratuberculosis are immunodominant Th1-type antigens in experimentally infected cattle [C] . Rosseels V, Marches S, Roupie V, International Colloquium on Paratuberculosis . 2007

机译：AG85来自分枝杆菌患者的培养滤液的同源物。对副伞菌在实验感染牛中的免疫肿瘤Th1型抗原
5. ECM33P is an Aspergillus fumigatus immunodominant antigen with cross reactivity to Rhizopus oryzae. [D] . Ngo, Anh T. N. 2013

机译：ECM33P是一种烟曲霉免疫优势抗原，与米根霉有交叉反应性。
6. Modulation of immunodominant sites in influenza hemagglutinin compromise antigenic variation and select receptor-binding variant viruses [O] . 1994

机译：流感血凝素中免疫优势位点的调节会损害抗原变异并选择受体结合变异病毒
7. Modulation of immunodominant sites in influenza hemagglutinin compromise antigenic variation and select receptor-binding variant viruses [O] . 1994

机译：流感血凝素中免疫优势位点的调节会损害抗原变异并选择受体结合变异病毒

Immunodominant Antigenic Sites in Primate Immunodeficiency Viruses and In vivoProtection

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