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首页> 美国政府科技报告 >Acute Light and Electron Microscopic Study of Ultraviolet 193-nm Excimer Laser Corneal Incisions
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Acute Light and Electron Microscopic Study of Ultraviolet 193-nm Excimer Laser Corneal Incisions

机译：紫外193nm准分子激光角膜切口的急性光和电子显微镜研究

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The 193-nm ultraviolet beam from an argon fluoride excimer laser was focused on the corneas of rabbits to produce incisions of the type necessary for radial keratotomy. The energy densities used were in two ranges, 1.0 to 2.1 J/sq cm per pulse and 200 to 700 mJ/sq cm per pulse. The eyes were enucleated and fixed for histologic and electron microscopic examination immediately after exposure. Structural analysis of the higher energy density exposures showed ridging on the surface of the cornea, micro-pitting on the stromal surface inside the cut, and denudation of the endothelium under the ablation zone. The lower energy density incisions did not exhibit significant surface riding or endothelial cell loss but did exhibit significant stromal swelling during the laser exposure thus making it difficult to produce incisions of a precisely controlled depth. Beam profile measurements and infrared thermal measurements of the cornea surface during laser exposure were made. Keywords: Ultraviolet lasers; Gas lasers; Laser applications; Laser surgery; Free electron lasers; Autoradiography; Reprints. (AW)

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