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The Role of Inflammation in Zinc,Amino Acid and Protein Alterations Induced by Zinc Chloride.

机译:炎症在氯化锌诱导的锌,氨基酸和蛋白质改变中的作用。

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The ip injection of zinc chloride (4-16mg/kg) produces a curvilinear increase in plasma zinc concentration, a linear increase in liver zinc content,and an increase in the hepatic uptake of C(14) aminoisobutyrate which ar significantly greater than control values. This dose range of ZnCl2also produces neutrophilia,increases in the plasma phenylalanine/tyrosine ratio and seromucoid and the appearance of alpha(2)-macrofetoprotein in the plasma,all of which are indicative of inflammation. It is suggested that some of the protective and metabolic effects ascribed to zinc may in fact be the result,at least in part,the inflammation which occurs when zinc salts are injected ip. (Author)

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