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首页> 美国政府科技报告 >Some Clinical and Immunological Observations on Domestic Animals Experimentally Infected with Toxoplasmosis.
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Some Clinical and Immunological Observations on Domestic Animals Experimentally Infected with Toxoplasmosis.

机译：实验性感染弓形虫病的家畜的临床和免疫学观察。

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Seven domestic animal species--including the cow (Bos taurus), buffalo (Syncerus caffer), camel (Camelus dromedarius), goat (Capra hircus), sheep (Ovis aries), pig (Sus scrofa) and the dog (Canis familiaris)--were experimentally infected with the Toxoplasma gondii RH strain. Blood samples were obtained from the animals prior to infection and at weekly intervals for from 10-16 weeks post inoculation. Sera were tested for toxoplasma antibodies by the indirect fluorescent antibody (IFA) test, the methylene blue dye (MBD) test, and the indirect hemagglutination (IHA) test. Goats developed the highest immunological response to the experimental infection as shown by the antibody titers detected by the 3 serological techniques used. The goat was the only species that developed dye test titers as high as 1:256 during a 16 week observation period. Buffalo and camel had poor immunological response. Toxoplasma antibodies were detected earlier by the IFA test than by the MBD and IHA test. The highest antibody levels were those detected by IFA test. With the exception of the camel and buffalo, the sera of the other species showed a nonspecific anti-sheep erythrocyte agglutinating reaction that interfered considerably with the IHA test results.

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