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Characterization of Tissue Ingrowth Into Porous Bioceramics

机译：组织向内生长为多孔生物陶瓷的表征

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A study of the tissue compatibility of the aluminum oxide implant material under different stress conditions in rabbits was performed over 4- and 8-week implantation periods. The specific objectives was to examine endosteal bone ingrowth into aluminum oxide cone-shaped stump plugs in amputated tibiae, while additional peelet-shaped implants in the tibiae and femur of rabbits with amputated and non-amputated limbs were studied to determine: (a) if the degree of loading placed on the amputated limb was sufficient to promote bone activity, (b) the degree of inertness and/or toxicity of the aluminum oxide implants, and (c) a possible cause of bone spurs. The results of the radiographic, histologic and microradiographic analyses of the in vivo implants demonstrated that there was little mineralized bone ingrowth into the cone-shaped aluminum oxide implants in the amputated tibiae. The study also showed that the aluminum oxide pellet implants in the tibiae and femur of the non-amputated limbs demonstrated excellent mineralized bone ingrowth into surface and internal pores. (Author)

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