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首页> 美国政府科技报告 >Dietary Regulation of Glycolytic Enzymes. Iv. Differential Hormonal Effects in Male and Female Rat Jejunum.
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Dietary Regulation of Glycolytic Enzymes. Iv. Differential Hormonal Effects in Male and Female Rat Jejunum.

机译：膳食调节糖酵解酶。四。雄性和雌性大鼠空肠中的差异激素效应。

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The effects of oral progesterone, diethylstilbestrol, 17 beta-estradiol and testosterone upon the activity of five enzymes involved in carbohydrate metabolism were studied in the jejunum of both male and female rats. In male rats, jejunal phosphofructokinase activites were in the following order: testosterone > estradiol > diethylstilbestrol > progesterone > control (P < 0.01). In female rats, jejunal phosphofructokinase activities were in the following order: estradiol > diethylstilbestrol > testosterone > progesterone > control (P < 0.01). In female rats, both progesterone and testosterone blocked the adaptive increases in jejunal phosphofructokinase and pyruvate kinase activites caused by estradiol alone. In male rates, in contrast, estradiol blocked the testosterone-produced adaptive increases in the jejunal phosphofructokinase and pyruvate kinase activites. The data implys that the response of the jejunal enzymes to sex hormones is determined in part by the sex of the animal. (Author)

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