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Integrative Functional Genomics and Proteomics to Uncover Mechanisms of Resistance to Chemotherapy in Ovarian Cancer.

机译：综合功能基因组学和蛋白质组学揭示卵巢癌化疗耐药机制。

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Ovarian cancer affects approximately 22,000 women and kills approximately 16,000 women each year in the United States. Resistance to chemotherapy is the major contributing factor in ovarian cancer-related death. The primary objective of this study is to gain mechanistic insights into the development of chemotherapy resistance in ovarian cancer. We expect that advances in this study will contribute to our understanding of chemotherapy resistance in ovarian cancer and will facilitate the development of more effective therapies to overcome the problems of chemotherapy resistance.

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作者
Chien, J.;
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年度 2011
页码 1-8
总页数 8
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Chemotherapy; Ovarian cancer; Resistance(Biology); Death; Genome; Therapy; Women;

机译：化疗;卵巢癌;抵抗（生物学）;死亡;基因组;治疗;女性;

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1. Integration of population and functional genomics to understand mechanisms of artemisinin resistance in Plasmodium falciparum [J] . Jenna Oberstaller, Linda Zoungrana, Carl D. Bannerman, International Journal for Parasitology: Drugs and Drug Resistance . 2021,第a期

机译：人口与功能基因组学的整合，以了解疟原虫抗性植物素抗性机制
2. Anti-cancer drug resistance: understanding the mechanisms through the use of integrative genomics and functional RNA interference. [J] . Tan DS, Gerlinger M, Teh BT, European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) . 2010,第12期

机译：抗癌药耐药性：通过使用整合基因组学和功能性RNA干扰了解机制。
3. How to improve the cost effectiveness of oncology drug development A commentary on Tan et al. Anti-cancer drug resistance--understanding the mechanisms through the use of integrative genomics and functional RNA interference. [J] . McCabe C, Smyth J European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) . 2010,第12期

机译：如何提高肿瘤药物开发的成本效益有关Tan等的评论。抗癌药物耐药性-通过使用综合基因组学和功能性RNA干扰了解机制。
4. An across Factor Normalization based SVD Approach to Analysis of Gene Expression Profiles for Uncovering Biomarkers in Ovarian Carcinoma Chemotherapy Responses [C] . Bin Han, Lei zhu, Yanchen, The 2nd International Conference on Bioinformatics and Biomedical Engineering(iCBBE 2008)(第二届生物信息与生物医学工程国际会议）论文集 . 2008

机译：基于跨因子归一化的SVD方法分析基因表达谱以发现卵巢癌化疗反应中的生物标志物
5. Integrating genomics and molecular biology: identifying transcriptional targets for the prostate cancer oncogene SOX4 and evaluating the efficacy of Aurora kinase inhibition in chemotherapy-resistant ovarian cancer [D] . Scharer, Christopher D. 2009

机译：整合基因组学和分子生物学：鉴定前列腺癌致癌基因SOX4的转录靶标并评估Aurora激酶抑制作用对化疗耐药的卵巢癌的疗效
6. Integration of population and functional genomics to understand mechanisms of artemisinin resistance in Plasmodium falciparum [O] . Jenna Oberstaller, Linda Zoungrana, Carl D. Bannerman, 2021

机译：人口与功能基因组学的整合了解疟原虫植物素抗性机制
7. Uncovering functional mechanisms in cancer through integrative genomics [O] . BANGARUSAMY DHINOTH KUMAR 2009

机译：通过整合基因组学揭示癌症的功能机制

Integrative Functional Genomics and Proteomics to Uncover Mechanisms of Resistance to Chemotherapy in Ovarian Cancer.

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