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首页> 美国政府科技报告 >Multidisciplinary Evaluation of Mild Traumatic Brain Injury: Early Predictors of Outcome
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Multidisciplinary Evaluation of Mild Traumatic Brain Injury: Early Predictors of Outcome

机译：轻度创伤性脑损伤的多学科评估：结果的早期预测因子

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The purpose of this study is to identify a cohort of patients with mild Traumatic Brain Injury and follow them for 1 year post injury to determine injury outcomes and identify factors that best predict long-term sequelae. The third year has been dedicated to continued subject recruitment and follow-up. Human subjects approval was obtained from both the University and Army review boards. Data entry and validation are an ongoing process which also includes data back-up and migration. Laboratory protocols continue for the collection, storage, and processing of blood samples for the S-100b tests. We have preliminary data on 108 samples. Preliminary data analysis has been initiated, as 43 of 80 one-year follow-up evaluations have been completed. As of March 31, 2006, 147 subjects have been recruited. Since current recruitment to date has fallen short of the original target of 300 subjects, a request for a no-cost extension through March 31, 2007, was filed on January 31, 2006, and approved February 8, 2006, which would allow continued recruitment of subjects through September 30, 2006. Adjusted target enrollment of 190-200 subjects with follow- up evaluations will continue through December 31, 2006.

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