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Bacillus anthracis Edema Toxin Inhibits Staphylococcus aureus Enterotoxin B Effects in Vitro: A Potential Protein Therapeutic

机译：炭疽杆菌水肿毒素抑制金黄色葡萄球菌肠毒素B的体外作用：潜在的蛋白质治疗

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Various in vitro effects of staphylococcal enterotoxin B (SEB) on human peripheral blood mononuclear cells were mitigated by Bacillus anthracis edema toxin. In particular, levels of some SEB-induced cytokines (tumor necrosis factor alpha, gamma interferon) and chemokines (monocyte chemoattractant protein 1, macrophage inflammatory protein 1 alpha MIP-1alpha, MIP-1beta) were significantly diminished or even nonexistent, depending upon the timing of edema toxin administration. Overall, these results suggest a novel use of B. anthracis edema toxin against a bacterial superantigen.

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作者
Krakauer, T. ; Little, S. F. ; Stiles, B. G.;
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年度 2005
页码 1-6
总页数 6
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Enterotoxins; Bacillus anthracis; Edema; In vitro analysis; Anthrax; Cytokines; Antigens; Staphylococcus; Exotoxins; Blood cells;

机译：肠毒素;炭疽芽孢杆菌;水肿;体外分析;炭疽;细胞因子;抗原;葡萄球菌;外毒素;血细胞;

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1. Bacillus anthracis Edema Toxin Inhibits Staphylococcus aureus Enterotoxin B Effects In Vitro: a Potential Protein Therapeutic? [J] . Teresa Krakauer, Stephen F. Little, Bradley G. Stiles Infection and immunity . 2005,第10期

机译：炭疽芽孢杆菌水肿毒素抑制金黄色葡萄球菌肠毒素B的体外作用：可能的蛋白质治疗方法？
2. Ebselen and analogs as inhibitors of Bacillus anthracis thioredoxin reductase and bactericidal antibacterials targeting Bacillus species, Staphylococcus aureus and Mycobacterium tuberculosis [J] . Gustafsson Tomas N., Osman Harer, Werngren Jim, Biochimica et Biophysica Acta. General Subjects . 2016,第6期

机译：Ebselen和类似物可作为炭疽芽孢杆菌硫氧还蛋白还原酶的抑制剂和针对芽孢杆菌属物种，金黄色葡萄球菌和结核分枝杆菌的杀菌剂
3. In silico modeling of the type 2 IDI enzymes of Bacillus licheniformis, Pseudomonas stutzeri, Streptococcus pyogenes, and Staphylococcus aureus for virtual screening of potential inhibitors of this therapeutic target [J] . Torktaz I., Shahbani Zahiri H., Akbari Noghabi K. Journal of molecular graphics & modelling . 2013,第Null期

机译：对地衣芽孢杆菌，斯氏假单胞菌，化脓性链球菌和金黄色葡萄球菌的2型IDI酶进行计算机模拟，以虚拟筛选该治疗靶点的潜在抑制剂
4. Recognition and Neutralization of Bacillus cereus Spores and Bacillus anthracis Toxins during Phagocytosis using Glycoconjugates [C] . Olga Tarasenko, Ashley Scott, Pierre Alusta PMSE Symposia . 2009

机译：使用甘油缀合物的吞噬作用期间芽孢杆菌孢子孢子和芽孢杆菌毒素的识别和中和
5. Solution Structures of Sortase A Transpeptidase from Bacillus anthracis and Staphylococcus aureus with Implications for Drug Design [D] . Weiner, Ethan Mark 2011

机译：炭疽芽孢杆菌和金黄色葡萄球菌Sortase A转肽酶的溶液结构及其对药物设计的影响
6. Bacillus anthracis Edema Toxin Inhibits Staphylococcus aureus Enterotoxin B Effects In Vitro: a Potential Protein Therapeutic? [O] . Teresa Krakauer, Stephen F. Little, Bradley G. Stiles 2005

机译：炭疽芽孢杆菌水肿毒素抑制金黄色葡萄球菌肠毒素B的体外作用：潜在的蛋白质治疗方法？
7. Bacillus anthracis Edema Toxin Inhibits Staphylococcus aureus Enterotoxin B Effects In Vitro: a Potential Protein Therapeutic? [O] . Krakauer, Teresa, Little, Stephen F., Stiles, Bradley G. 2005

机译：炭疽芽孢杆菌水肿毒素抑制金黄色葡萄球菌肠毒素B的体外作用：潜在的蛋白质治疗方法？

Bacillus anthracis Edema Toxin Inhibits Staphylococcus aureus Enterotoxin B Effects in Vitro: A Potential Protein Therapeutic

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