首页> 美国政府科技报告 >Optimal Treatment of Malignant Long Bone Fracture: Influence of Method of Repair and External Beam Irradiation on the Pathway and Efficacy of Fracture Healing.
【24h】

Optimal Treatment of Malignant Long Bone Fracture: Influence of Method of Repair and External Beam Irradiation on the Pathway and Efficacy of Fracture Healing.

机译:[中华创伤骨科杂志Chinese Journal of Orthopaedic Trauma]张莹莹,王玮 - 恶性长骨骨折的优化治疗:修复方法和外照射对骨折愈合的途径和疗效的影响。

获取原文

摘要

The purpose of this project is to characterize the differential effects of radiation on the two pathways of fracture healing in an established animal model of bilateral femur fracture repair. Since relocation to MUSC, the PI has been fully engaged in securing suitable facilities, collaborations, and related institutional regulatory approvals to implement the animal model at MUSC. This was accomplished in August, 2013. Surgical procedures consisting of bilateral femur fracture and repair have been completed on both cohorts of 18 animals in the year 1 SOW; all animals were imaged and have been sacrificed according to protocol schedule. Group I specimens are being analyzed with micro CT to assess callus volume and character. Group II specimens are being processed for RNA isolation and PCR array analysis. Year 2 SOW animal procedures in Group III will begin on schedule in the fifth quarter of the award.

著录项

相似文献

  • 外文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号