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Protection against UVA-induced photooxidative damage in mammalian cell lines expressing increased levels of metallothionein.

机译：在表达增加水平的金属硫蛋白的哺乳动物细胞系中防止UVa诱导的光氧化损伤。

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Metallothionein (MT) is an endogenous low molecular weight protein that is inducible in a variety of eukaryotic cells and has the ability to selectivity bind heavy metal ions such as zinc and the cadmium. Although the exact physiological role of MT is sti ...

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作者
E. J. Dudek J. G. Peak M. J. Peak R. M. Roth;
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年度 1990
页码 1-8
总页数 8
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Animal Cells; Biological Functions; Biological Radiation Effects; Cadmium 109; Cadmium Chlorides; Cell Cultures; Cell Killing; Clone Cells; DNA damage; Dose-Response Relationships; EDB/560120; Enzyme Induction; Fibroblasts; Free radicals; Lethal Irradiation; Meetings; Messenger RNA; Metallothionein; Near Ultraviolet Radiation; Radiation Protection; Radioprotective Substances; Response Modifying Factors; Survival Curves; Tritium; Zinc Compounds;

机译：动物细胞;生物功能;生物辐射效应;镉109;氯化镉;细胞培养;细胞杀伤;克隆细胞; DNa损伤;剂量 - 反应关系; EDB / 560120;酶诱导;成纤维细胞;自由基;致死辐射;会议;信使RNa;金属硫蛋白;近紫外辐射;辐射防护;辐射防护物质;响应修正因子;存活曲线;氚;锌化合物;

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1. Placing the RPL32 Promoter Upstream of a Second Promoter Results in a Strongly Increased Number of Stably Transfected Mammalian Cell Lines That Display High Protein Expression Levels [J] . F.Hoeksema, K.Hamer, M.Siep, Biotechnology Research International . 2011,第1期

机译：将RPL32启动子置于第二个启动子的上游会导致稳定转染的哺乳动物细胞系数量显着增加，这些细胞系显示出高蛋白表达水平
2. GC Content of Early Metazoan Genes and Its Impact on Gene Expression Levels in Mammalian Cell Lines [J] . Ismail Sahin Gul, Jens Staal, Paco Hulpiau, Genome Biology and Evolution . 2018,第3期

机译：早期后生动物基因的GC含量及其对哺乳动物细胞系基因表达水平的影响
3. High levels of protein expression using different mammalian CMV promoters in several cell lines [J] . Xia W, Bringmann P, McClary J, Protein Expression and Purification . 2006,第1期

机译：在几种细胞系中使用不同的哺乳动物CMV启动子进行高水平的蛋白质表达
4. Rational drug design using mammalian cell lines expressing site-directed mutants of the human H_1 histaminic receptor [C] . Moguilevsky N., Differding E., Gillard M., Annual Meeting of the Japanese Association for Animal Cell Technology . 1998

机译：使用哺乳动物细胞系的理性药物设计表达人H_1组蛋白受体的点定向突变体
5. Putrescine-mediated changes in mammalian intracellular polyamine levels increase spermidine/spermine-N1-acetyltransferase activity and increase gene expression of several cell cycle-related genes. [D] . Ancheta, Allan Atienza. 2010

机译：腐胺介导的哺乳动物细胞内多胺水平的变化增加了亚精胺/亚精胺-N1-乙酰基转移酶的活性，并增加了几种细胞周期相关基因的基因表达。
6. Placing the RPL32 Promoter Upstream of a Second Promoter Results in a Strongly Increased Number of Stably Transfected Mammalian Cell Lines That Display High Protein Expression Levels [O] . F. Hoeksema, K. Hamer, M. Siep, 2011

机译：将RPL32启动子置于第二个启动子的上游会导致稳定转染的哺乳动物细胞系数量显着增加这些细胞系显示出高蛋白表达水平
7. Protection against UVA-induced photooxidative damage in mammalian cell lines expressing increased levels of metallothionein [O] . Edward J. Dudek, Jennifer G. Peak, Robert M. Roth, 1990

机译：对哺乳动物细胞系的UVA诱导的光氧化损伤的保护表达含量增加的金属硫蛋白水平
8. Protection against UVA-induced photooxidative damage in mammalian cell lines expressing increased levels of metallothionein [R] . Dudek, E. J., Peak, J. G., Peak, M. J., 1990

机译：在表达增加水平的金属硫蛋白的哺乳动物细胞系中防止UVa诱导的光氧化损伤

Protection against UVA-induced photooxidative damage in mammalian cell lines expressing increased levels of metallothionein.

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