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Report of International Workshop on Gastrointestinal Absorption of Actinides and Other Metals Held at Seattle, WA on 24 June 1985

机译:1985年6月24日在华盛顿州西雅图举行的act系元素及其他金属胃肠吸收国际研讨会报告

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Current knowledge of the fraction of ingested actinide absorbed from the gastrointestinal (GI) tract, and of factors influencing that fraction absorbed, is probably adequate for the establishment of safe limits for the exposure of workers. Uncertainties necessitate a degree of probable overprotection that is often costly. Our knowledge of factors that may influence actinide absorption by members of the more heterogeneous general population is in a less satisfactory state, particularly with regard to the infant and to other groups with dietary habits or medical treatment regimens that differ from the norm. Further investigation in several research areas is required to support more realistic occupational limits and to evaluate and regulate the exposure of general populations. This report includes summaries of various topics. Among these topics are limited studies of actinide absorption in human volunteers that would provide the critical data needed for intelligent extrapolation of results from past and future studies with experimental animals; studies to further our understanding of the basic physiological mechanisms involved in the transport of actinides into, and across, the intestinal epithelium; and studies with experimental animals in preparation for studies with human volunteers. (ERA citation 13:006536)

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