• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国政府科技报告 >Screening Human Populations for Chromosome Damage. Progress Report, March 1982-November 1982
【24h】

Screening Human Populations for Chromosome Damage. Progress Report, March 1982-November 1982

机译：筛选人类群体的染色体损伤。进展报告，1982年3月至1982年11月

获取原文
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The micronuclear counts in 73 relatively young and healthy patients obtained in previous studies were examined. The natural logarithm of the micronuclear counts (LMNC) was approximately normally distributed so we have tested the effects of age, sex, and medical x-ray exposure on the counts. The results show a clear dependence of micronuclear counts on age, and demonstrate that studies of chromosome damage in radiation workers or in other populations exposed to radiation may be misinterpreted if the effects of age and medical x-ray examinations are not controlled. The results also show that the variability in LNMC among the individuals examined cannot be accounted for totally by the factors of age, sex, or medical x-rays. There are at least two other important sources of variation: counting statistics and degree of lymphocyte proliferation. A single set of harlequin stained cells may be sufficient for estimating micronuclear yields, the degree of lymphocyte proliferation, and possibly the frequency of chromosome aberrations. These results point to the usefulness of the micronucleus assay for screening human populations for chromosome damage. (ERA citation 08:030474)

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号