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Adrenal Scintigraphy. An Experimental Study and Clinical Application

机译:肾上腺闪烁扫描术。实验研究与临床应用

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The visualization of functioning adrenocortical tissue by scintigraphy became possible with the introduction of radioiodinated cholesterol derivatives. According to the literature, there is evidence that one of these iodinated cholesterols, 6- beta -iodomethyl-nor-cholesterol, concentrates in the adrenal cortex to a much greater extent than exp 131 I-19-odocholesterol. Results comparing both radiopharmaceuticals are described. The authors investigated the possibility of increasing the uptake of iodinated cholesterol using simultaneous ACTH and the 'cholesterol side-chain cleavage enzymeblocker': aminoglutethimide. The results of adrenal scintigraphy performed in 37 patients are described. Finally, the literature on adrenal scintigraphy is reviewed, and results reported in various studies are compared. (Atomindex citation 10:445422)

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