3-D Model of Signaling and Transport Pathways in Epithelial Cells

机译：上皮细胞信号传导途径的三维模型

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A 3-dimensional computer model was developed to simulate the spatial and chemical evolution of calcium ions inside an array of human epithelial kidney cells. This is a prototype model, intended to develop a methodology to incorporate much more complex interactions of metabolic and other processes within many types of cells and lead to increased ability to predict cellular responses to disease as well as to chemical and biological warfare situations. Preliminary tests of the model are described.

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作者
Quong, A.; Westbrook, C.;
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年度 2005
页码 1-14
总页数 14
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Biological warfare ; Cells(Biology) ; Pathways ; Three dimensional models ; Signaling ; Transport ; Diseases ; Kidneys ; Calcium ions ; Simulation ; Compter models;

机译：生物战;细胞（生物学）;途径;三维模型;信号传导;运输;疾病;肾脏;钙离子;模拟;计算机模型;

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机译：Spalt转录因子在Decapentaplegic信号通路的下游调节细胞增殖，存活和上皮完整性Spalt转录因子在Decapentaplegic信号通路的下游调节细胞增殖，存活和上皮完整性Spalt转录因子在Decapentaplegic信号通路的下游调节细胞增殖，存活和上皮完整性Decapentaplegic信号通路
2. Cell Signaling Pathways Mediating Epidermal Growth Factor Stimulation of Na:K:2Cl Cotransport Activity in Rabbit Corneal Epithelial Cells [J] . H. Yang, Z. Wang, Y. Miyamoto, The Journal of Membrane Biology . 2001,第2期

机译：介导表皮生长因子刺激兔角膜上皮细胞中Na：K：2Cl共转运的细胞信号通路
3. Cell signaling pathways mediating epidermal growth factor stimulation of Na:K:2Cl cotransport activity in rabbit corneal epithelial cells. [J] . Yang H, Wang Z, Miyamoto Y, The Journal of Membrane Biology: An International Journal for Studies on the Structure, Function & Genesis of Biomembranes . 2001,第2期

机译：介导表皮生长因子刺激兔角膜上皮细胞Na：K：2Cl共转运活性的细胞信号通路。
4. Cell-matrix mechanical signaling pathways in pulmonary alveolar epithelial cells [C] . Susan S. Margulies, Michele Hawk, Valerie M. Weaver Bioengineering Conference . 2001

机译：肺肺泡上皮细胞中的细胞 - 矩阵机械信号通路
5. Polarity and proliferation are controlled by distinct signaling pathways downstream of PI3-kinase in breast epithelial tumor cells: Functional bifurcation of PI3-kinase signaling pathway. [D] . Liu, Hong. 2005

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6. Fluid flow induces mechanosensitive ATP release calcium signalling and Cl− transport in biliary epithelial cells through a PKCζ-dependent pathway [O] . Kangmee Woo, Amal K Dutta, Vishal Patel, 2008

机译：液流通过PKCζ依赖性途径诱导胆管上皮细胞中机械敏感性ATP释放钙信号传导和Cl-转运
7. ATP‑binding cassette transporter A7 accelerates epithelial‑to‑mesenchymal transition in ovarian cancer cells by upregulating the transforming growth factor‑β signaling pathway [O] . Xia Liu, Qing Li, Jing Zhou, 2018

机译：ATP结合盒式传递器A7通过上调转化生长因子-β信号通路加速在卵巢癌细胞中的上皮 - 间充质转变

3-D Model of Signaling and Transport Pathways in Epithelial Cells

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