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Biosynthesis of long-chain dicarboxylic acid monomers from renewable resources.211 Final technical report

机译:来自可再生资源的长链二羧酸单体的生物合成.211最终技术报告

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Long-chain aliphatic alpha omega dicarboxylic, acids (diacids) are used in a wide211u001evariety of plastics and other chemical applications. Long-chain diacids are 211u001ealmost exclusively produced by chemical conversion processes that suffer a number 211u001eof disadvantages, including limitations in the range of products, use of multi-211u001estep conversion processes, dependence on non-renewable feedstocks, and generation 211u001eof unwanted and hazardous byproducts. Biotechnology offers an innovative way to 211u001eovercome the limitations and disadvantages of the chemical processes to make 211u001ediacids. Yeast biocatalyst are able to convert long-chain fatty acids, which are 211u001ereadily available from renewable agricultural products, directly to long-chain 211u001ediacids. The biocatalyst can produce a variety of diacid products and produces no 211u001ehazardous byproducts. However, development efforts are needed to realize the 211u001epotential of this biosynthetic approach to the production of long-chain diacids. 211u001eThe objective of this program was to develop and demonstrate key biocatalyst and 211u001ebioprocess technology to produce cost-competitive long-chain diacids from 211u001eagricultural products, and to demonstrate the suitability of the diacids as 211u001ecomonomers in a high melt flow polymer application.

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