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首页> 美国政府科技报告 >Clinical Effect of Toothbrushing with 0.4% Stannous Fluoride Gel on Periodontal Health
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Clinical Effect of Toothbrushing with 0.4% Stannous Fluoride Gel on Periodontal Health

机译：0.4％氟化亚锡凝胶刷牙治疗牙周健康的临床效果

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The purpose of the study was to determine the effect of toothbrushing with 0.4 percent SnF2 or 0.22 percent NaF gel on clinical and microbial parameters associated with gingivitis. 281 subjects (mean GI=1.62) were randomly divided into 3 groups. Subjects were instructed to brush with an ADA accepted fluoride dentifrice twice daily and subsequently toothbrush with 0.4 percent SnF2 (n=89), 0.22 percent NaF (n=87) or a placebo fluoride-free gel (n=87). At baseline, 6, 12 and 18 months, clinical and microbial data were collected from FDI teeth numbers 16, 21, 24, 36, 41 and 44. At 6, 12 and 18 months, cocci were increased and motile rods, gingival index and bleeding decreased when compared to baseline for all groups (p equals or is less than 0.05). Spirochetes were only decreased for SnF2 and NaF groups at six months. More stain was detected in the SnF2 group than the other groups at all time periods except baseline (p equals or is less than 0.001). No differences were observed in gingival index and percent sites bleeding in the SnF2 or NaF groups when compared to the placebo group at 18 months.

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