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Clinical Pharmacology Study of Intraoral Fluoride Releasing Devices

机译:口内氟释放装置的临床药理学研究

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Forty adolescent subjects were each fitted with two fluoride releasing devices fastened to molar teeth. One group was fitted with devices that released .05 mg F/day; the other, 1.0 mg F/day. Devices were tolerated well but breakage was a problem. The concentration of fluoride in the saliva was elevated but not in serum. The .05 group had elevated urine fluoride. The 1.0 group did not. Fluoride concentration of plaque appeared elevated.

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