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Fluid Dynamics of Blood Cells and Applications to Hemodialysis.

机译:血细胞的流体动力学及其在血液透析中的应用。

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The annual report describes results of a cooperative effort on the development of a blood access device for chronic hemodialysis. The access consists of titanium 'Tee'bonded to a blood flow channel of either dacron graft,autogenous artery graft or external artery wrap. The external artery wrap technique has been tried on thirteen dogs. Problems have occurred in the bonding of the arterial wall to the dacron fabric in the area of the needle puncture and further work has been discontinued. Autogenous artery grafts were formed in situ with a Sparks mandril. Fourteen dogs have had the device implanted and nine have been hooked up as A-V shunts. Results were not encouraging. Clotting was seen in four dogs due to pseudointimal proliferation in the graft. The access device with polytetrafluorethylene (PTFE) blood channel has been implanted in eight dogs. With the exception of two dogs lost to incisional wound infection,these grafts have functioned well. Fistulogram of one dog with Conray-40and a rapid sequence x-ray machine showed the A-V channel to be perfectly clean. One dog was electively autopsied after over three months of having a functioning graft.

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