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Design and Fabrication of a Blood Oxygenator for Circulatory Assist Devices

机译:用于循环辅助装置的血液氧合器的设计和制造

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The report describes the result of a program to utilize a new industrial copolymer for fashioning disposable membrane envelopes and measuring their performance in blood test circuits. The membrane, XD polymer, is of special interest because it consists of polycarbonate (Lexan) methyl silicone. It has about one-third the oxygen and carbon dioxide permeability of methyl silicone. It is strong, may be heat-sealed, can be commercially fabricated, and should eventually be relatively inexpensive. In addition, the material may be solvent-cast in special molds to produce patterned membranes. Envelopes of plain membrane and membrane with a support pattern have been used in the Peirce-Galletti lung both without a change in design and with modification of the Silastic support mats in order to reduce the blood flow path from 12 to 6 centimeters. Significantly improved oxygen exchange resulted both from the use of a support pattern and from shortening the flow path. Demonstrable advantages of a membrane lung include diminished blood trauma and stable low extracorporeal blood volume. (Author)

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