首页> 美国政府科技报告 >A COMPARATIVE STUDY OF SEROLOGIC TECHNIQUES FOR THE DETECTION OF ANTILEUCOCYTE ANTIBODIES AND CORRELATION OF THE RESULTS OBTAINED WITH THE RESPONSE TO SKIN HOMOGRAFTS IN HUMAN SUBJECTS.
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A COMPARATIVE STUDY OF SEROLOGIC TECHNIQUES FOR THE DETECTION OF ANTILEUCOCYTE ANTIBODIES AND CORRELATION OF THE RESULTS OBTAINED WITH THE RESPONSE TO SKIN HOMOGRAFTS IN HUMAN SUBJECTS.

机译:抗人类细胞抗体检测的血清学技术比较研究及人体皮肤同种异体反应的相关性。

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1,620sera from multiparous women or polytransfused patients were tested for their anti-leucocyte or platelet activity. 47sera were collected for study. 5new individuals received skin grafts and leucocytes from unrelated subjects. 4developed antibodies. 17other volunteers were immunized by skin grafts following intra-dermal injections of leucocyte cytoplasm extracts (TTA of F.T. RAPAPORT). 8 developed antibodies which are now under study. 25absorption experiments were performed using 30positive cells. The genetic study of the Hu-1system was pursued on Caucasian, Negro and Asiatic populations in Paris and in New York in collaboration with F.T. RAPAPORT. Family studies were carried out showing no independent segregation between the leucocyte antigens of the Hu-1system. Typing of acute leukemic patients did not show any difference in the frequency of the antigens studied. Typed,purified,stabilized antigens prepared were also studied. (Author)

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