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首页> 外文OA文献 >Drug therapy problems among patients with cardiovascular disease admitted to the medical ward and had a follow-up at the ambulatory clinic of Hiwot Fana Specialized University Hospital: The case of a tertiary hospital in eastern Ethiopia
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Drug therapy problems among patients with cardiovascular disease admitted to the medical ward and had a follow-up at the ambulatory clinic of Hiwot Fana Specialized University Hospital: The case of a tertiary hospital in eastern Ethiopia

机译：患有医疗病房的心血管疾病患者药物治疗问题，并在HIWOT Fana专业大学医院的动态诊所进行了后续行动：东埃塞俄比亚东部院校的案例

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Background: Pharmacotherapy is important in reducing morbidity and mortality related to cardiovascular diseases. However, these advantages are limited by drug therapy problems that can impact on a patient’s quality of life, prolong hospital stays, and increase the overall burden of healthcare expenditures. Therefore, this study was aimed to assess drug therapy problems among patients with cardiovascular diseases who were hospitalized and received follow-up at the ambulatory clinic of Hiwot Fana Specialized University Hospital. Methods: An institution-based cross-sectional study design was used to collect data from patients with cardiovascular diseases who were admitted to the medical ward and those who had received follow-up at the ambulatory clinic of Hiwot Fana Specialized University Hospital. The collected data were coded, entered, and analyzed using SPSS version 16. The associations of selected categorical variables were done using binary logistic and multivariate logistic regression analyses. Results: Out of 216 study participants, females accounted for 123 (57%), whereas 93 (43%) of them were males. Among cardiovascular diseases identified in the medical ward and ambulatory clinics of Hiwot Fana Specialized University Hospital, congestive heart failure 96 (44.4%) and hypertension 93 (43.1%) were the two most commonly diagnosed disorders. Of the total participants involved in the study, 131 (60.65%) had drug therapy problems. Among the seven classes of drug therapy problems assessed, the most commonly observed was the need for additional drug therapy 76 (58%); followed by cases related to unnecessary drug therapy and noncompliance both of which were estimated to be 16 (12.2%). In addition, of independent variables, only the use of more than three drugs was significantly associated in both binary logistic (crude odds ratio = 0.41, 95% confidence interval = 0.234–0.719, p = 0.002) and multivariate logistic regressions (adjusted odds ratio = 4.86, 95% confidence interval = 1.625–14.536, p = 0.005) as compared with those patients who were using less than three drugs. Conclusion: The findings of the study indicated that more than half of the study participants experienced drug therapy problems, for which 58% required additional drug therapy. The risk of drug therapy problem is found to increase with the use of more than three drugs. Since these problems are adversely affecting the treatment outcome of patients, this is an area which requires special attention and the cooperation of healthcare professionals to tackle it.
机译：背景：药物疗法在降低与心血管疾病相关的发病率和死亡率方面是重要的。然而，这些优势受到可能影响患者的生活质量，延长医院的药物治疗问题的限制，并提高了医疗保健支出的总体负担。因此，本研究旨在评估在HIWOT Fana专业大学医院HIWOT Fana专业大学医院的医疗诊所住院和接受后续的心血管疾病患者的药物治疗问题。方法：基于机构的横截面研究设计用于收集来自入院的心血管疾病患者的数据以及接受HIWOT Fana专业大学医院的动态诊所所接受后续行动的人。使用SPSS版本16编码，输入并分析收集的数据。使用二进制逻辑和多变量逻辑回归分析完成所选分类变量的关联。结果：在216名研究参与者中，女性占123（57％），而其中93名（43％）是男性。在HIWOT Fana专业大学医院的医学病房和动态诊所确定的心血管疾病中，充血性心力衰竭96（44.4％）和高血压93（43.1％）是最常见的疾病。在研究中参与的总参与者中，131名（60.65％）有药物治疗问题。在评估的七种药物治疗问题中，最常见的是需要额外的药物治疗76（58％）;其次是与不必要的药物治疗相关的病例，其两者均估计为16（12.2％）。另外，在二进制物流（粗次数= 0.41,95％置信区间= 0.234-0.719，P = 0.002）和多变量逻辑回归中，仅使用超过三种药物的使用显着相关（粗略赔率比= 0.234-0.719）和多变量逻辑回归（调整的赔率比与使用少于三种药物的患者相比，= 4.86,95％置信区间= 1.625-14.536，p = 0.005）。结论：研究结果表明，一半以上的研究参与者经历了药物治疗问题，其中58％需要额外的药物治疗。发现药物治疗问题的风险随着三种以上的药物而增加。由于这些问题对患者的治疗结果产生了不利影响，因此这是一个需要特别关注和医疗保健专业人员的合作的领域。

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  • 作者

    Tamene Gelchu; Jemal Abdela;

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  • 年度 2019
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